Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that may cause life-
threatening diseases and some minor infections in living organisms. However, it shows …

The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is
still based on diagnostic procedures that fulfill the clinical need to differentiate between …

Increasing bacterial drug resistance to antibiotics has posed a major threat to contemporary
public health, which resulted in a large number of people suffering from serious infections …

Vancomycin is a glycopeptide antibiotic that is active against Gram-positive bacteria,
including methicillin-resistant Staphylococcus aureus. Nephrotoxicity, which is usually …

Antimicrobial resistance seriously threatened human health. Combination therapy is
generally an effective strategy to fight resistance, while some data on its effects are …

Traditional methods employed to discover new antibiotics are both a time-consuming and
financially-taxing venture. This has led researchers to mine existing libraries of clinical …

Conventional wisdom holds that the best way to treat infection with antibiotics is to 'hit early
and hit hard'. A favoured strategy is to deploy two antibiotics that produce a stronger effect in …

Surgical implant-associated bone infections (osteomyelitis) have severe clinical and
socioeconomic consequences. Treatment of chronic bone infections often involves …

Infections with rapidly evolving pathogens are often treated using combinations of drugs with
different mechanisms of action. One of the major goal of combination therapy is to reduce …

OBJECTIVE: Methicillin-resistant Staphylococcus aureus (MRSA) is associated with difficult-
to-treat infections and high levels of morbidity. Manual practitioners work in environments …