Host-directed immunotherapy of viral and bacterial infections: past, present and future

RS Wallis, A O'Garra, A Sher, A Wack - Nature Reviews Immunology, 2023 - nature.com
The advent of COVID-19 and the persistent threat of infectious diseases such as
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …

[PDF][PDF] Tuberculosis among HIV patients: a review of Prevalence and Associated Factors

EI Obeagu, EC Onuoha - Int. J. Adv. Res. Biol. Sci, 2023 - researchgate.net
Tuberculosis (TB) is a chronic infectious disease that has represented a major health
problem over the centuries and it has accounted for more human misery, suffering and loss …

Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease …

CJL Murray, KF Ortblad, C Guinovart, SS Lim… - The Lancet, 2014 - thelancet.com
Summary Background The Millennium Declaration in 2000 brought special global attention
to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal …

Global report: UNAIDS report on the global AIDS epidemic 2013

Joint United Nations Programme on HIV/AIDS - 2013 - policycommons.net
[198] p.: graphs, maps, tablesThe 2013 report on the global AIDS epidemic contains the
latest data on numbers of new HIV infections, numbers of people receiving antiretroviral …

HIV and tuberculosis: a deadly human syndemic

CK Kwan, JD Ernst - Clinical microbiology reviews, 2011 - Am Soc Microbiol
SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

HIV-associated lung disease

I Konstantinidis, K Crothers, KM Kunisaki… - Nature Reviews …, 2023 - nature.com
Lung disease encompasses acute, infectious processes and chronic, non-infectious
processes such as chronic obstructive pulmonary disease, asthma and lung cancer. People …

Advancing host-directed therapy for tuberculosis

RS Wallis, R Hafner - Nature Reviews Immunology, 2015 - nature.com
Improved treatments are needed for nearly all forms of Mycobacterium tuberculosis infection.
Adjunctive host-directed therapies have the potential to shorten tuberculosis treatment …

Antiretroviral therapy for prevention of tuberculosis in adults with HIV: a systematic review and meta-analysis

AB Suthar, SD Lawn, J Del Amo, H Getahun, C Dye… - 2012 - journals.plos.org
Background Human immunodeficiency virus (HIV) infection is the strongest risk factor for
developing tuberculosis and has fuelled its resurgence, especially in sub-Saharan Africa. In …

Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa

NR Gandhi, A Moll, AW Sturm, R Pawinski, T Govender… - The Lancet, 2006 - thelancet.com
Background The epidemics of HIV-1 and tuberculosis in South Africa are closely related.
High mortality rates in co-infected patients have improved with antiretroviral therapy, but …

Understanding latent tuberculosis: a moving target

PL Lin, JAL Flynn - The Journal of Immunology, 2010 - journals.aai.org
Tuberculosis (TB) remains a threat to the health of people worldwide. Infection with
Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection …