Cashew apple bagasse as a support for the immobilization of lipase B from Candida antarctica: Application to the chemoenzymatic production of (R)-Indanol

TC de Souza, TS Fonseca, JA da Costa… - Journal of Molecular …, 2016 - Elsevier
Lipase B from Candida antarctica lipase expressed in Aspergillus niger has been covalently
immobilized on cashew apple bagasse, and it stability and performance in the …

Promiscuous lipase catalyzed a new P–C bond formation: Green and efficient protocol for one‐pot synthesis of α‐aminophosphonates

S Guezane‐Lakoud, M Toffano… - Heteroatom …, 2017 - Wiley Online Library
Abstract α‐Aminophosphonates are valuable substructures with important biological and
pharmacological properties. Lipase catalytic promiscuity is a new method in the organic …

Diastereoselective synthesis of bis (α-aminophosphonates) by lipase catalytic promiscuity

R Aissa, S Guezane-Lakoud, E Kolodziej… - New Journal of …, 2019 - pubs.rsc.org
New bis (α-aminophosphonates) were directly prepared with high diastereoselectivity by
lipase catalytic promiscuity in the presence of immobilized Candida antarctica lipase. We …

Enantioselective esterification of (R,S)-flurbiprofen catalyzed by lipase in ionic liquid

R Zhao, X Zhang, L Zheng, H Xu… - Green Chemistry Letters …, 2017 - Taylor & Francis
The enantioselective esterification of (R, S)-flurbiprofen catalyzed by Candida sp. lipase
(CSL)(a cheap commercial lipase) was successfully conducted in ionic liquid (IL). The …

Chemoenzymatic synthesis of luliconazole mediated by lipases

TS Fonseca, LD Lima, MCF de Oliveira… - European Journal of …, 2018 - Wiley Online Library
A straightforward chemoenzymatic synthesis of luliconazole has been developed. The key
step involved the preparation of the enantiomerically pure β‐halohydrin (1S)‐2‐chloro‐1‐(2 …

Biochemical characterization, substrate and stereoselectivity of an outer surface putative α/β hydrolase from the pathogenic Leptospira

UN Shankar, SK Padhi, M Akif - International Journal of Biological …, 2023 - Elsevier
The genome of pathogenic leptospira encodes a plethora of outer surface and secretory
proteins. The outer surface or secreted α/β hydrolases in a few pathogenic organisms are …

Efficient access to both enantiomers of 3‐(1‐hydroxyethyl)phenol by regioselective and enantioselective CAL‐B–catalyzed hydrolysis of diacetate in organic media …

N Braia, M Merabet‐Khelassi, L Aribi‐Zouioueche - Chirality, 2018 - Wiley Online Library
In the present paper, we describe several pathways employing immobilized lipase from
Candida antarctica B (CAL‐B) as biocatalyst to prepare easily both enantiomers of 3‐(1 …

Enhancing lipases reactivity in benzylic acetates hydrolysis: impact of kosmotropic salts under non-conventional conditions

N Braia, F Larit, M Merabet-Khelassi - Biocatalysis and …, 2024 - Taylor & Francis
The effect of four kosmotropic salts additives, namely Na2CO3, Na2SO4, Na2HPO4, and
NaCl, on the reactivity and selectivity of immobilized Candida antarctica lipase B (CAL-B) …

[HTML][HTML] Fluorogenic kinetic assay for high-throughput discovery of stereoselective ketoreductases relevant to pharmaceutical synthesis

YC Thai, A Szekrenyi, Y Qi, GW Black… - Bioorganic & Medicinal …, 2018 - Elsevier
Abstract Enantiomerically pure 1-(6-methoxynaphth-2-yl) and 1-(6-(dimethylamino) naphth-2-
yl) carbinols are fluorogenic substrates for aldo/keto reductase (KRED) enzymes, which …

Diastereoselective and enantioselective alkaline-hydrolysis of 2-aryl-1-cyclohexyl acetate: a CAL-B catalyzed deacylation/acylation tandem process

FZ Belkacemi, M Merabet-Khelassi… - Tetrahedron …, 2017 - Elsevier
Candida antarctica lipase proved to be a particularly efficient lipase for the resolution of
racemic 2-arylcyclohexyl acetate in hydrolysis reaction with Na 2 CO 3 in an organic …