Role of VEGF-A and LRG1 in abnormal angiogenesis associated with diabetic nephropathy

A Zhang, H Fang, J Chen, L He, Y Chen - Frontiers in physiology, 2020 - frontiersin.org
Diabetic nephropathy (DN) is an important public health concern of increasing proportions
and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the …

Worsening proteinuria and renal function after intravitreal vascular endothelial growth factor blockade for diabetic proliferative retinopathy

M Shye, RM Hanna, SS Patel, N Tram-Tran… - Clinical Kidney …, 2020 - academic.oup.com
Systemic vascular endothelial growth factor (VEGF) inhibitions can induce worsening
hypertension, proteinuria and glomerular diseases of various types. These agents can also …

Systemic adverse events among patients with diabetes treated with intravitreal anti–vascular endothelial growth factor injections

S Zafar, A Walder, S Virani, K Biggerstaff… - JAMA …, 2023 - jamanetwork.com
Importance Anti–vascular endothelial growth factor (VEGF) agents are currently the
mainstay of treatment for diabetic retinopathy (DR). Although effective, data on their systemic …

Review of intravitreal VEGF inhibitor toxicity and report of collapsing FSGS with TMA in a patient with age-related macular degeneration

G Phadke, RM Hanna, A Ferrey, EA Torres… - Clinical kidney …, 2021 - academic.oup.com
Intravitreal vascular endothelial growth factor (VEGF) receptor blockade is used for a variety
of retinal pathologies. These include age-related macular degeneration (AMD), diabetic …

Do intravitreal anti-vascular endothelial growth factor agents lead to renal adverse events? A pharmacovigilance real-world study

L Jiang, L Peng, Y Zhou, G Chen, B Zhao, M Li… - Frontiers in …, 2023 - frontiersin.org
Purpose Intravitreal vascular endothelial growth factor (VEGF) blockade is essential in many
macular edema diseases treatment. However, intravitreal VEGF treatment has been …

[HTML][HTML] Risk of renal damage associated with intravitreal anti-VEGF therapy for diabetic macular edema in routine clinical practice

MP del Cura, MJC Carballés… - Indian Journal of …, 2023 - journals.lww.com
Purpose: Vascular endothelial growth factor inhibitors (anti-VEGF) have been shown to be
effective in the treatment of diabetic macular edema. However, there is little information …

Intravitreal vascular endothelial growth factors hypertension, proteinuria, and renal injury: a concise review

RM Hanna, RS Ahdoot, MS Kim… - Current opinion in …, 2022 - journals.lww.com
Intravitreal vascular endothelial growth factors hypertensio... : Current Opinion in
Nephrology and Hypertension Intravitreal vascular endothelial growth factors hypertension …

Membranoproliferative glomerulonephritis after intravitreal vascular growth factor inhibitor injections: A case report and review of the literature

G Gan, M Michel, A Max… - British Journal of …, 2023 - Wiley Online Library
Systemic administration of agents that inhibit vascular endothelial growth factor (VEGF) and
therefore vascular proliferation is often used to treat various cancers. However, these agents …

Intravitreal vascular endothelial growth factor inhibitor use and renal function decline in patients with diabetic retinopathy

SH Ou, CH Yin, TL Chung, HY Chen, CL Chen… - International Journal of …, 2022 - mdpi.com
Adverse renal effects of systemic vascular endothelial growth factor (VEGF) inhibitor
treatment are well documented. We aimed to identify associations between intravitreal VEGF …

[HTML][HTML] Similar Risk of Kidney Failure among Patients with Blinding Diseases Who Receive Ranibizumab, Aflibercept, and Bevacizumab: An Observational Health …

CX Cai, A Nishimura, MG Bowring, E Westlund… - Ophthalmology …, 2024 - Elsevier
Purpose To characterize the incidence of kidney failure associated with intravitreal anti-
VEGF exposure; and compare the risk of kidney failure in patients treated with ranibizumab …