The growth plate (GP) is a cartilaginous region situated between the epiphysis and
metaphysis at the end of the immature long bone, which is susceptible to mechanical …

Diverse cell types in the central nervous system (CNS) are generated by a relatively small
pool of neural stem cells during early development. Spatial and temporal regulation of stem …

Although radiotherapy is a well-known effective non-surgical treatment for malignant
gliomas, the therapeutic efficacy is severely limited due to the radioresistance of tumor cells …

Introduction Dysregulation of the Hippo signaling pathway has been implicated in multiple
pathologies, including cancer, and YAP1 is the major effector of the pathway. In this study …

Summary N 6-methyladenosine (m 6 A) modification controls cell fate determination. Here,
we show that liquid-liquid phase separation (LLPS) of YTH N 6-methyladenosine RNA …

Most adult hippocampal neural stem cells (NSCs) remain quiescent, with only a minor
portion undergoing active proliferation and neurogenesis. The molecular mechanisms that …

The formation of three-dimensional ordered spatial patterns, which is essential for
embryonic development, tissue regeneration, and cancer metastasis, is mainly guided by …

The ability to reproduce scientific findings is foundational in research; yet, it is compromised
in part by poorly characterized reagents, including antibodies. In this report, we describe the …

The Hippo pathway is an evolutionarily conserved kinase cascade that controls organ size
by regulating cell proliferation, differentiation, migration, and apoptosis. Activation of the …