The bioavailability, extraction, biosynthesis and distribution of natural dihydrochalcone: Phloridzin

L Tian, J Cao, T Zhao, Y Liu, A Khan… - International journal of …, 2021 - mdpi.com
Phloridzin is an important phytochemical which was first isolated from the bark of apple
trees. It is a member of the dihydrochalcones and mainly distributed in the plants of the …

Alibertia patinoi (Cuatrec.) Delprete & CHPerss. (Borojó): food safety, phytochemicals, and aphrodisiac potential

N González-Jaramillo, N Bailon-Moscoso… - SN Applied …, 2023 - Springer
Although the western discovery of borojó [Alibertia patinoi Cuatrec.(Delprete & CH Perss.)] is
as recent as 1948, its several traditional uses in gastronomy and medicine, and its fame as …

Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis

J Cheng, D Liu, Y Huang, L Chen, Y Li… - Journal of Agricultural …, 2023 - ACS Publications
Phlorizin (PHZ) is the main active component of apple peel and presents a potential
application value. In the past few years, some reports have suggested that PHZ may have …

Role of glucose-lowering medications in erectile dysfunction

A Cignarelli, VA Genchi, R D'Oria, F Giordano… - Journal of clinical …, 2021 - mdpi.com
Erectile dysfunction (ED) is a long-term complication of type 2 diabetes (T2D) widely known
to affect the quality of life. Several aspects of altered metabolism in individuals with T2D may …

Phlorizin from sweet tea inhibits the progress of esophageal cancer by antagonizing the JAK2/STAT3 signaling pathway

Z Jia, Y Xie, H Wu, Z Wang, A Li, Z Li… - Oncology …, 2021 - spandidos-publications.com
Phlorizin, an important member of the dihydrochalcone family, has been widely used as a
Chinese Traditional Medicine for treatment of numerous diseases. The present study aimed …

Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in high-fat and high-fructose diet-induced obese male mice

S Zhang, X Wang, S Liu, C Hu, Y Meng - Brain, Behavior, and Immunity, 2025 - Elsevier
The long-term high-fat, high-sugar diet exacerbates type 2 diabetes mellitus (T2DM)-related
cognitive impairments. Phlorizin, a well-studied natural compound found in apples and other …

Maternal Hyperglycemia Induces Autonomic Dysfunction and Heart Failure in Older Adult Offspring

OA da Silva, GP Duarte, S Lahlou - Experimental and Clinical …, 2023 - thieme-connect.com
Aims Offspring exposed to an adverse fetal environment, such as gestational diabetes, may
manifest increased susceptibility to several chronic diseases later in life. In the present …

Causal association between antidiabetic drugs and erectile dysfunction: evidence from Mendelian randomization

L Feng, W Jinhua, G Shulin, X Jiangping… - Frontiers in …, 2024 - frontiersin.org
Background Antidiabetic drugs are widely used in clinical practice as essential drugs for the
treatment of diabetes. The effect of hypoglycemic drugs on erectile dysfunction has not been …

Phloridzin: Advances on resources, biosynthetic pathway, bioavailability, bioactivity, and pharmacology

D Abouelenein, G Caprioli, AM Mustafa - Handbook of Dietary Flavonoids, 2023 - Springer
Flavonoids are polyphenolic molecules that are produced as bioactive secondary
metabolites in plants and are responsible for its color, taste, and biological effects. Fruit and …

[PDF][PDF] 基于主客体作用的根皮苷药物可控释放研究

高芳, 王东明, 丁玮泽, 郑媛洁 - 高分子通报, 2023 - gfztb.com
根皮苷在新型药物和天然保健食品开发中具有广泛的应用前景, 因其成分的复杂性和低溶解性,
对根皮苷的研究极具挑战性. 本文通过核磁共振, 紫外可见光谱及荧光发射光谱等检测手段 …