[HTML][HTML] Toxicity of gold nanoparticles (AuNPs): A review

A Sani, C Cao, D Cui - Biochemistry and biophysics reports, 2021 - Elsevier
Gold nanoparticles are a kind of nanomaterials that have received great interest in field of
biomedicine due to their electrical, mechanical, thermal, chemical and optical properties …

Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems

M Rezaee, RK Oskuee, H Nassirli… - Journal of Controlled …, 2016 - Elsevier
Efficient gene therapy is mainly dependent on the gene transfer capability of gene delivery
vectors. Non-viral vectors have become the research interest of many researchers because …

[HTML][HTML] The application of carbon nanotubes in target drug delivery systems for cancer therapies

W Zhang, Z Zhang, Y Zhang - Nanoscale research letters, 2011 - Springer
Among all cancer treatment options, chemotherapy continues to play a major role in killing
free cancer cells and removing undetectable tumor micro-focuses. Although chemotherapies …

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy

E Miele, GP Spinelli, E Miele, E Di Fabrizio… - International journal …, 2012 - Taylor & Francis
During recent decades there have been remarkable advances and profound changes in
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …

[HTML][HTML] Nonviral delivery systems for antisense oligonucleotide therapeutics

S Huang, XY Hao, YJ Li, JY Wu, DX Xiang, S Luo - Biomaterials Research, 2022 - Springer
Antisense oligonucleotides (ASOs) are an important tool for the treatment of many genetic
disorders. However, similar to other gene drugs, vectors are often required to protect them …

Endosomal escape: a bottleneck in intracellular delivery

HK Shete, RH Prabhu… - Journal of nanoscience …, 2014 - ingentaconnect.com
With advances in therapeutic science, apart from drugs, newer bioactive moieties like
oligonucleotides, proteins, peptides, enzymes and antibodies are constantly being …

[PDF][PDF] The toxicity of Gold Nanoparticles in relation to their physiochemical properties.

CS Yah - Biomedical Research (0970-938X), 2013 - researchgate.net
The rapid emergence of gold nanoparticles (AuNPs) technology holds great promise for
future applications due to their large volume specific surface areas with high diverse surface …

Effect of size on biological properties of nanoparticles employed in gene delivery

S Prabha, G Arya, R Chandra, B Ahmed… - Artificial cells …, 2016 - Taylor & Francis
Context The size of nanoparticles plays a pivotal role in determining the gene delivery
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …

[HTML][HTML] Dendrimers for siRNA delivery

S Biswas, VP Torchilin - Pharmaceuticals, 2013 - mdpi.com
Since the discovery of the “starburst polymer”, later renamed as dendrimer, this class of
polymers has gained considerable attention for numerous biomedical applications, due …

Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors

W Jeong, A Rapisarda, SR Park, RJ Kinders… - Cancer chemotherapy …, 2014 - Springer
Abstract Purpose Hypoxia-inducible factor-1 (HIF-1) facilitates the adaptation of normal and
tumor tissues to oxygen deprivation. HIF-1 is frequently overexpressed in cancer cells …