In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …

Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …

Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Drug resistance is well-defined as a serious problem in our living world. To survive,
microbes develop defense strategies against antimicrobial drugs. Drugs exhibit less or no …

The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

The emergence of bacterial resistance has motivated researchers to discover new
antibacterial agents. Nowadays, fluoroquinolones keep their status as one of the essential …

COVID-19 patients are at increased risk of secondary bacterial and fungal infections due to
factors such as prolonged intubation, ubiquitous use of invasive catheters, and impaired …

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Hydroxamic acids are an important class of molecules, in particular because of their metal-
chelating ability. Microorganisms, including pathogenic bacteria, use hydroxamate-based …