Chloroplast translation: structural and functional organization, operational control, and regulation

R Zoschke, R Bock - The Plant Cell, 2018 - academic.oup.com
Chloroplast translation is essential for cellular viability and plant development. Its positioning
at the intersection of organellar RNA and protein metabolism makes it a unique point for the …

Engineering plastid genomes: methods, tools, and applications in basic research and biotechnology

R Bock - Annual Review of Plant Biology, 2015 - annualreviews.org
The small bacterial-type genome of the plastid (chloroplast) can be engineered by genetic
transformation, generating cells and plants with transgenic plastid genomes, also referred to …

Engineering α-carboxysomes into plant chloroplasts to support autotrophic photosynthesis

T Chen, M Hojka, P Davey, Y Sun, GF Dykes… - Nature …, 2023 - nature.com
The growth in world population, climate change, and resource scarcity necessitate a
sustainable increase in crop productivity. Photosynthesis in major crops is limited by the …

Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids

J Zhang, SA Khan, C Hasse, S Ruf, DG Heckel, R Bock - Science, 2015 - science.org
Double-stranded RNAs (dsRNAs) targeted against essential genes can trigger a lethal RNA
interference (RNAi) response in insect pests. The application of this concept in plant …

A faster Rubisco with potential to increase photosynthesis in crops

MT Lin, A Occhialini, PJ Andralojc, MAJ Parry… - Nature, 2014 - nature.com
In photosynthetic organisms, d-ribulose-1, 5-bisphosphate carboxylase/oxygenase
(Rubisco) is the major enzyme assimilating atmospheric CO2 into the biosphere. Owing to …

A new synthetic biology approach allows transfer of an entire metabolic pathway from a medicinal plant to a biomass crop

P Fuentes, F Zhou, A Erban, D Karcher, J Kopka… - elife, 2016 - elifesciences.org
Artemisinin-based therapies are the only effective treatment for malaria, the most
devastating disease in human history. To meet the growing demand for artemisinin and …

Producing fast and active Rubisco in tobacco to enhance photosynthesis

T Chen, S Riaz, P Davey, Z Zhao, Y Sun… - The Plant …, 2023 - academic.oup.com
Abstract Ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco) performs most of the
carbon fixation on Earth. However, plant Rubisco is an intrinsically inefficient enzyme given …

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic

M Oey, M Lohse, B Kreikemeyer, R Bock - The plant journal, 2009 - Wiley Online Library
Plastids (chloroplasts) possess an enormous capacity to synthesize and accumulate foreign
proteins. Here we have maximized chloroplast protein production by over‐expressing a …

Engineering chloroplasts to improve Rubisco catalysis: prospects for translating improvements into food and fiber crops

RE Sharwood - New Phytologist, 2017 - Wiley Online Library
The uncertainty of future climate change is placing pressure on cropping systems to
continue to provide stable increases in productive yields. To mitigate future climates and the …

Expression strategies for the efficient synthesis of antimicrobial peptides in plastids

MP Hoelscher, J Forner, S Calderone, C Krämer… - Nature …, 2022 - nature.com
Antimicrobial peptides (AMPs) kill microbes or inhibit their growth and are promising next-
generation antibiotics. Harnessing their full potential as antimicrobial agents will require …