Quantitative MRI and spectroscopy of bone marrow

DC Karampinos, S Ruschke… - Journal of Magnetic …, 2018 - Wiley Online Library
Bone marrow is one of the largest organs in the human body, enclosing adipocytes,
hematopoietic stem cells, which are responsible for blood cell production, and mesenchymal …

MRI‐based quantitative osteoporosis imaging at the spine and femur

N Sollmann, MT Löffler, S Kronthaler… - Journal of Magnetic …, 2021 - Wiley Online Library
Osteoporosis is a systemic skeletal disease with a high prevalence worldwide, characterized
by low bone mass and microarchitectural deterioration, predisposing an individual to fragility …

Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the methodologies …

J Tratwal, R Labella, N Bravenboer… - Frontiers in …, 2020 - frontiersin.org
The interest in bone marrow adiposity (BMA) has increased over the last decade due to its
association with, and potential role, in a range of diseases (osteoporosis, diabetes …

The role of bone marrow fat in skeletal health: usefulness and perspectives for clinicians

J Paccou, P Hardouin, A Cotten… - The Journal of Clinical …, 2015 - academic.oup.com
Context: There is growing interest in the relationship between bone marrow fat (BMF), bone
mineral density (BMD), and fractures. Moreover, BMF might be influenced by metabolic …

Anatomical variation of age-related changes in vertebral bone marrow composition using chemical shift encoding-based water–fat magnetic resonance imaging

T Baum, A Rohrmeier, J Syväri… - Frontiers in …, 2018 - frontiersin.org
Assessment of vertebral bone marrow composition has been proposed as imaging
biomarker for osteoporosis, hematopoietic, and metabolic disorders. We investigated the …

MR-based assessment of bone marrow fat in osteoporosis, diabetes, and obesity

C Cordes, T Baum, M Dieckmeyer, S Ruschke… - Frontiers in …, 2016 - frontiersin.org
Bone consists of the mineralized component (ie, cortex and trabeculae) and the non-
mineralized component (ie, bone marrow). Most of the routine clinical bone imaging uses X …

MR-based assessment of body fat distribution and characteristics

T Baum, C Cordes, M Dieckmeyer, S Ruschke… - European Journal of …, 2016 - Elsevier
The assessment of body fat distribution and characteristics using magnetic resonance (MR)
methods has recently gained significant attention as it further extends our …

Bone marrow adipose tissue in metabolic health

G Pachón-Peña, MA Bredella - Trends in Endocrinology & Metabolism, 2022 - cell.com
Recent studies have highlighted the role of bone marrow adipose tissue (BMAT) as a
regulator of skeletal homeostasis and energy metabolism. While long considered an inert …

Gender-and age-associated differences in bone marrow adipose tissue and bone marrow fat unsaturation throughout the skeleton, quantified using chemical shift …

KM Beekman, M Regenboog, AJ Nederveen… - Frontiers in …, 2022 - frontiersin.org
Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with
osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to …

Bone marrow absorbed doses and correlations with hematologic response during 177Lu-DOTATATE treatments are influenced by image-based dosimetry method …

L Hagmarker, J Svensson, T Rydén… - Journal of Nuclear …, 2019 - Soc Nuclear Med
This study aimed to compare different image-based methods for bone marrow dosimetry and
study the dose–response relationship during treatment with 177Lu-DOTATATE in patients …