Advances in the design and development of SARS-CoV-2 vaccines

XL Peng, JSY Cheng, HL Gong, MD Yuan… - Military Medical …, 2021 - Springer
Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The RNA …

Comprehensive review on current interventions, diagnostics, and nanotechnology perspectives against SARS-CoV-2

DS Chauhan, R Prasad, R Srivastava… - Bioconjugate …, 2020 - ACS Publications
The coronavirus disease 2019 (COVID-19) has dramatically challenged the healthcare
system of almost all countries. The authorities are struggling to minimize the mortality along …

SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern

M Lu, M Chamblee, Y Zhang, C Ye… - Proceedings of the …, 2022 - National Acad Sciences
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the main target for neutralizing antibodies (NAbs). The S protein trimer is anchored in the …

Mucosal and systemic neutralizing antibodies to norovirus induced in infant mice orally inoculated with recombinant rotaviruses

T Kawagishi, L Sánchez-Tacuba… - Proceedings of the …, 2023 - National Acad Sciences
Rotaviruses (RVs) preferentially replicate in the small intestine and frequently cause severe
diarrheal disease, and the following enteric infection generally induces variable levels of …

Norovirus: facts and reflections from past, present, and future

Y Lucero, DO Matson, S Ashkenazi, S George… - Viruses, 2021 - mdpi.com
Human Norovirus is currently the main viral cause of acute gastroenteritis (AGEs) in most
countries worldwide. Nearly 50 years after the discovery of the “Norwalk virus” by Kapikian …

Inactivation of a human norovirus surrogate, human norovirus virus-like particles, and vesicular stomatitis virus by gamma irradiation

K Feng, E Divers, Y Ma, J Li - Applied and environmental …, 2011 - Am Soc Microbiol
Gamma irradiation is a nonthermal processing technology that has been used for the
preservation of a variety of food products. This technology has been shown to effectively …

Enhanced removal of a human norovirus surrogate from fresh vegetables and fruits by a combination of surfactants and sanitizers

A Predmore, J Li - Applied and environmental microbiology, 2011 - Am Soc Microbiol
Fruits and vegetables are major vehicles for transmission of food-borne enteric viruses since
they are easily contaminated at pre-and postharvest stages and they undergo little or no …

Understanding the relationship between norovirus diversity and immunity

LA Ford-Siltz, K Tohma, GI Parra - Gut microbes, 2021 - Taylor & Francis
Human noroviruses are the most common viral cause of acute gastroenteritis worldwide.
Currently, there are no approved vaccines or specific therapeutics to treat the disease. Some …

Norovirus vaccines under development

Y Lucero, R Vidal - Vaccine, 2018 - Elsevier
Noroviruses (NoVs) are one of the leading causes of acute gastroenteritis, including both
outbreaks and endemic infections. The development of preventive strategies, including …

Plant viruses as nanoparticle-based vaccines and adjuvants

MÈ Lebel, K Chartrand, D Leclerc, A Lamarre - Vaccines, 2015 - mdpi.com
Vaccines are considered one of the greatest medical achievements in the battle against
infectious diseases. However, the intractability of various diseases such as hepatitis C …