[HTML][HTML] Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

J Hu, Z Zhang, WJ Shen, S Azhar - Nutrition & metabolism, 2010 - Springer
Steroid hormones regulate diverse physiological functions such as reproduction, blood salt
balance, maintenance of secondary sexual characteristics, response to stress, neuronal …

Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL

VI Zannis, A Chroni, M Krieger - Journal of molecular medicine, 2006 - Springer
The concentration, composition, shape, and size of plasma high-density lipoprotein (HDL)
are determined by numerous proteins that influence its biogenesis, remodeling, and …

[PDF][PDF] Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function.

WJ Shen, S Asthana, FB Kraemer, S Azhar - Journal of lipid research, 2018 - academia.edu
Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for
many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective …

[PDF][PDF] HDL biogenesis, remodeling, and catabolism

VI Zannis, P Fotakis, G Koukos, D Kardassis… - Handb Exp …, 2015 - library.oapen.org
In this chapter, we review how HDL is generated, remodeled, and catabolized in plasma. We
describe key features of the proteins that participate in these processes, emphasizing how …

[HTML][HTML] Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps

VLD Thi, C Granier, MB Zeisel, M Guérin… - Journal of Biological …, 2012 - ASBMB
Hepatitis C virus (HCV) particles assemble along the very low density lipoprotein pathway
and are released from hepatocytes as entities varying in their degree of lipid and …

[HTML][HTML] Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra-and extra-cellular domains

M Dreux, VL Dao Thi, J Fresquet, M Guérin… - PLoS …, 2009 - journals.plos.org
HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of
HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by …

[HTML][HTML] SR-B1's next top model: structural perspectives on the functions of the HDL receptor

HR Powers, D Sahoo - Current atherosclerosis reports, 2022 - Springer
Abstract Purpose of Review The binding of high-density lipoprotein (HDL) to its primary
receptor, scavenger receptor class B type 1 (SR-B1), is critical for lowering plasma …

Endothelial scavenger receptors

H Adachi, M Tsujimoto - Progress in lipid research, 2006 - Elsevier
In the past few decades, cDNAs for endothelial scavenger receptors that bind to negatively
charged molecules, particularly acetylated low density lipoproteins (Ac-LDL), have been …

SR-B1 and PDZK1: partners in HDL regulation

BL Trigatti - Current opinion in lipidology, 2017 - journals.lww.com
Identification of carriers of rare mutations in human SCARB1 and PDZK1 that impair the
function of their gene products and characterization of the effects of these mutations on HDL …

[HTML][HTML] Functional characterization of newly-discovered mutations in human SR-BI

AC Chadwick, D Sahoo - 2012 - journals.plos.org
In rodents, SR-BI has been firmly established as a physiologically relevant HDL receptor that
mediates removal of HDL-cholesteryl esters (CE). However, its role in human lipoprotein …