Hyperuricemia and its related diseases: mechanisms and advances in therapy
L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …
[HTML][HTML] Nonalcoholic fatty liver disease: a precursor of the metabolic syndrome
The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …
manifestation of the metabolic syndrome” is outdated. We identified and summarized …
[HTML][HTML] The role of xanthine oxidoreductase and uric acid in metabolic syndrome
Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …
through the oxidative stress and the inflammatory response induced by XOR-derived …
Allopurinol hypersensitivity: a systematic review of all published cases, 1950–2012
SN Ramasamy, CS Korb-Wells, DRW Kannangara… - Drug safety, 2013 - Springer
Background Allopurinol is the primary therapy for the management of chronic gout.
Utilization of allopurinol has increased in tandem with the growing prevalence of gout …
Utilization of allopurinol has increased in tandem with the growing prevalence of gout …
[HTML][HTML] Metabolic syndrome and cancer risk: the role of xanthine oxidoreductase
Obesity and related pathologies such as diabetes and metabolic syndrome are associated
with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is …
with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is …
Dose-response relationship of serum uric acid with metabolic syndrome and non-alcoholic fatty liver disease incidence: a meta-analysis of prospective studies
Z Liu, S Que, L Zhou, S Zheng - Scientific Reports, 2015 - nature.com
Emerging evidence has shown that serum uric acid (SUA) elevation might cause metabolic
derangements, including metabolic syndrome (MetS) and non-alcoholic fatty liver disease …
derangements, including metabolic syndrome (MetS) and non-alcoholic fatty liver disease …
Serum uric acid: a strong and independent predictor of metabolic syndrome after adjusting for body composition
Background Some observational studies have suggested that serum uric acid (SUA) levels
are one of the determinants of the metabolic syndrome (MetS). However, previous studies …
are one of the determinants of the metabolic syndrome (MetS). However, previous studies …
A confirmatory factor analysis of the metabolic syndrome in adolescents: an examination of sex and racial/ethnic differences
Abstract Objective The metabolic syndrome (MetS) is a cluster of clinical indices that signals
increased risk for cardiovascular disease and Type 2 diabetes. The diagnosis of MetS is …
increased risk for cardiovascular disease and Type 2 diabetes. The diagnosis of MetS is …
Elevated serum uric acid and risk of cardiovascular or all-cause mortality in people with suspected or definite coronary artery disease: a meta-analysis
R Wang, Y Song, Y Yan, Z Ding - Atherosclerosis, 2016 - Elsevier
Background and aims Serum uric acid (SUA) has been recognized as an independent risk
factor for mortality in the general population. We performed this meta-analysis to determine …
factor for mortality in the general population. We performed this meta-analysis to determine …
Association between metabolic syndrome and uric acid: a systematic review and meta-analysis
E Raya-Cano, M Vaquero-Abellán, R Molina-Luque… - Scientific Reports, 2022 - nature.com
This systematic review and meta-analysis aim to provide the best evidence on the
association between metabolic syndrome (MetS) and uric acid (UA) by determining the size …
association between metabolic syndrome (MetS) and uric acid (UA) by determining the size …