Sex differences may play a critical role in modulating how chronic or heavy alcohol use
impacts the brain to cause the development of alcohol use disorder (AUD). AUD is a …

Substance use disorders (SUDs) are one of the leading causes of morbidity and mortality
worldwide. In spite of considerable advances in understanding the neural underpinnings of …

The purpose of this review is to discuss ways to think about and study sex differences in
preclinical animal models. We use the framework of addiction, in which animal models have …

The factors causing the transition from recreational drug consumption to addiction remain
largely unknown. It has not been tested whether dopamine (DA) is sufficient to trigger this …

Background The high prevalence and burden to society of drug abuse and addiction is
undisputed. However, its conceptualisation as a brain disease is controversial, and …

Background and aims Research into work addiction has steadily grown over the past
decade. However, the literature is far from unified and there has been much debate on many …

Compulsive eating behavior is a transdiagnostic construct that is characteristic of medical
and psychiatric conditions such as forms of obesity and eating disorders. Although feeding …

Negative urgency is a unique dimension of impulsivity that involves acting rashly when in
extreme distress and impairments in inhibitory control. It has been hypothesized to derive …

Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-
seeking associated with several drugs of abuse and thus represents a promising …

Fibromyalgia and opioid use disorder (OUD) are highly impactful chronic illnesses with
substantially overlapping psychosocial, biological, and clinical features. Little previous …