Spreading depression, spreading depolarizations, and the cerebral vasculature

C Ayata, M Lauritzen - Physiological reviews, 2015 - journals.physiology.org
Spreading depression (SD) is a transient wave of near-complete neuronal and glial
depolarization associated with massive transmembrane ionic and water shifts. It is …

Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations

D Pietrobon, MA Moskowitz - Nature Reviews Neuroscience, 2014 - nature.com
Punctuated episodes of spreading depolarizations erupt in the brain, encumbering tissue
structure and function, and raising fascinating unanswered questions concerning their …

Mitochondria and neuronal activity

O Kann, R Kovács - American Journal of Physiology-Cell …, 2007 - journals.physiology.org
Mitochondria are central for various cellular processes that include ATP production,
intracellular Ca2+ signaling, and generation of reactive oxygen species. Neurons critically …

The neural basis of functional brain imaging signals

D Attwell, C Iadecola - Trends in neurosciences, 2002 - cell.com
The haemodynamic responses to neural activity that underlie the blood-oxygen-level-
dependent (BOLD) signal used in functional magnetic resonance imaging (fMRI) of the brain …

Carbon dioxide and the cerebral circulation

JE Brian - The Journal of the American Society of …, 1998 - pubs.asahq.org
THE arterial partial pressure of carbon dioxide (Pa CO (2)) is an important regulator of the
cerebral circulation, and a large body of literature describes this relation. This review …

Vasoconstrictive neurovascular coupling during focal ischemic depolarizations

HK Shin, AK Dunn, PB Jones… - Journal of Cerebral …, 2006 - journals.sagepub.com
Ischemic depolarizing events, such as repetitive spontaneous periinfarct spreading
depolarizations (PIDs), expand the infarct size after experimental middle cerebral artery …

Nitric Oxide Scavenging by Hemoglobin or Nitric Oxide Synthase Inhibition by N-Nitro-L-Arginine Induces Cortical Spreading Ischemia When K+ Is Increased in the …

JP Dreier, K Körner, N Ebert, A Görner… - Journal of Cerebral …, 1998 - journals.sagepub.com
We investigated the combined effect of increased brain topical K+ concentration and
reduction of the nitric oxide (NO.) level caused by nitric oxide scavenging or nitric oxide …

Electrophysiological correlates of the BOLD signal for EEG‐informed fMRI

T Murta, M Leite, DW Carmichael… - Human brain …, 2015 - Wiley Online Library
Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) are
important tools in cognitive and clinical neuroscience. Combined EEG–fMRI has been …

Regional variation in brain capillary density and vascular response to ischemia

M Cavaglia, SM Dombrowski, J Drazba, A Vasanji… - Brain research, 2001 - Elsevier
Differences in brain neuroarchitecture have been extensively studied and recent results
demonstrated that regional differences in the physiological properties of glial cells are …

Products of hemolysis in the subarachnoid space inducing spreading ischemia in the cortex and focal necrosis in rats: a model for delayed ischemic neurological …

JP Dreier, N Ebert, J Priller, D Megow, U Lindauer… - Journal of …, 2000 - thejns.org
Object. The pathogenesis of delayed ischemic neurological deficits after subarachnoid
hemorrhage has been related to products of hemolysis. Topical brain superfusion of artificial …