One in 4 Americans> 40 years of age takes a statin to reduce the risk of myocardial
infarction, ischemic stroke, and other complications of atherosclerotic disease. The most …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Aims To objectively appraise evidence for possible adverse effects of long-term statin
therapy on glucose homeostasis, cognitive, renal and hepatic function, and risk for …

Statins, inhibitors of the hydroxymethylglutaryl-CoA (HMG-CoA) reductase enzyme, are
molecules of fungal origin. By inhibiting a key step in the sterol biosynthetic pathway statins …

Evidence-based update of the Cataract in the Adult Eye Preferred Practice Pattern®(PPP)
guidelines, describing the prevalence, risk factors, and natural history of cataract …

Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …

Preferred Practice Pattern® guidelines are developed by the Academy's H. Dunbar Hoskins
Jr., MD Center for Quality Eye Care without any external financial support. Authors and …

Background: Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies can
reduce low-density lipoprotein cholesterol (LDL-C) to very low levels when added to …

Background Familial hypercholesterolemia is one of the most common inherited metabolic
diseases and is an autosomal dominant disorder meaning heterozygotes, or carriers, are …

Although statin therapy has proven to be the cornerstone for prevention and treatment of
cardiovascular disease (CVD), there are many patients for whom long-term therapy remains …