The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with high morbidity and
mortality worldwide. To date, limited therapeutic achievements targeting cell proliferation …

As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …

Ischemic stroke is caused by insufficient cerebrovascular blood and oxygen supply. It is a
major contributor to death or disability worldwide and has become a heavy societal and …

Cardiac function is required for blood circulation and systemic oxygen delivery. However,
the heart has intrinsic oxygen demands that must be met to maintain effective contractility …

The extracellular matrix (ECM) surrounds cells in the brain, providing structural and
functional support. Emerging studies demonstrate that the ECM plays important roles during …

A purified spike (S) glycoprotein of severe acute respiratory syndrome-related coronavirus 2
(SARS-CoV-2) coronavirus was used to study its effects on THP-1 macrophages, peripheral …

Myeloid-derived suppressor cells (MDSCs) expand in tumor-bearing host. They suppress
anti-tumor immune response and promote tumor growth. Chemokines play a vital role in …

Hypoxia is a common condition found in a wide range of solid tumors and is often
associated with poor prognosis. Hypoxia increases tumor glycolysis, angiogenesis, and …

Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …