[HTML][HTML] Measles virus host invasion and pathogenesis

BM Laksono, RD De Vries, S McQuaid, WP Duprex… - Viruses, 2016 - mdpi.com
Measles virus is a highly contagious negative strand RNA virus that is transmitted via the
respiratory route and causes systemic disease in previously unexposed humans and non …

[HTML][HTML] Peste des petits ruminants virus infection of small ruminants: a comprehensive review

N Kumar, S Maherchandani, SK Kashyap, SV Singh… - Viruses, 2014 - mdpi.com
Peste des petits ruminants (PPR) is caused by a Morbillivirus that belongs to the family
Paramyxoviridae. PPR is an acute, highly contagious and fatal disease primarily affecting …

Adherens junction protein nectin-4 is the epithelial receptor for measles virus

MD Mühlebach, M Mateo, PL Sinn, S Prüfer, KM Uhlig… - Nature, 2011 - nature.com
Measles virus is an aerosol-transmitted virus that affects more than 10 million children each
year and accounts for approximately 120,000 deaths,. Although it was long believed to …

[HTML][HTML] Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus

RS Noyce, DG Bondre, MN Ha, LT Lin, G Sisson… - PLoS …, 2011 - journals.plos.org
Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to
infect many human cell lines. However, wild type isolates of measles virus cannot use CD46 …

New viruses for cancer therapy: meeting clinical needs

TS Miest, R Cattaneo - Nature reviews microbiology, 2014 - nature.com
Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus
platforms, and viruses from three families have progressed to advanced efficacy trials. In …

Authentic modeling of human respiratory virus infection in human pluripotent stem cell-derived lung organoids

M Porotto, M Ferren, YW Chen, Y Siu, N Makhsous… - MBio, 2019 - Am Soc Microbiol
Infectious viruses so precisely fit their hosts that the study of natural viral infection depends
on host-specific mechanisms that affect viral infection. For human parainfluenza virus 3, a …

[HTML][HTML] Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry

LT Lin, TY Chen, SC Lin, CY Chung, TC Lin… - BMC microbiology, 2013 - Springer
Background We previously identified two hydrolyzable tannins, chebulagic acid (CHLA) and
punicalagin (PUG) that blocked herpes simplex virus type 1 (HSV-1) entry and spread …

[HTML][HTML] Tropism and molecular pathogenesis of canine distemper virus

S Rendon-Marin, R da Fontoura Budaszewski… - Virology journal, 2019 - Springer
Background Canine distemper virus (CDV), currently termed Canine morbillivirus, is an
extremely contagious disease that affects dogs. It is identified as a multiple cell tropism …

Designing and building oncolytic viruses

J Maroun, M Muñoz-Alía, A Ammayappan… - Future …, 2017 - Taylor & Francis
Oncolytic viruses (OVs) are engineered and/or evolved to propagate selectively in
cancerous tissues. They have a dual mechanism of action; direct killing of infected cancer …

Structure of the measles virus hemagglutinin bound to its cellular receptor SLAM

T Hashiguchi, T Ose, M Kubota, N Maita… - Nature structural & …, 2011 - nature.com
Measles virus, a major cause of childhood morbidity and mortality worldwide, predominantly
infects immune cells using signaling lymphocyte activation molecule (SLAM) as a cellular …