New insights into the pathobiology and treatment of chronic myelogenous leukemia

CV Cotta, CE Bueso-Ramos - Annals of Diagnostic Pathology, 2007 - Elsevier
Chronic myelogenous leukemia (CML) is one of the most frequently diagnosed forms of
leukemia. Recent advances in the understanding of the molecular mechanisms involved in …

Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts

C Sillaber, M Mayerhofer, H Agis, V Sagaster… - Wiener Klinische …, 2003 - Springer
Chronic myeloid leukemia (CML) is a stem cell disease characterized by excessive
accumulation of clonal myeloid (precursor) cells in hematopoietic tissues. CML cells display …

[图书][B] Flow cytometry of hematological malignancies

C Ortolani - 2021 - books.google.com
Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to
the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow …

Immunophenotypic profile of acute leukemia: critical analysis and insights gained at a tertiary care center in India

S Gujral, Y Badrinath, A Kumar… - Cytometry Part B …, 2009 - Wiley Online Library
Background To analyze the spectrum of various types and subtypes of acute leukemia.
Methods Two thousand five hundred and eleven consecutive new referral cases of acute …

[图书][B] Atlas of differential diagnosis in neoplastic hematopathology

W Gorczyca - 2021 - taylorfrancis.com
This atlas presents not only the differential diagnosis but also the detailed morphologic,
immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid …

Phenotype of blasts in chronic myeloid leukemia in blastic phase—Analysis of bone marrow trephine biopsies and correlation with cytogenetics

AG Reid, VA De Melo, K Elderfield, I Clark, D Marin… - Leukemia research, 2009 - Elsevier
We identified different phenotypic subsets among 62 cases of chronic myeloid leukemia
(CML) in blast crisis (BC)(26% B-lymphoblastic, and 74% various myeloblastic subsets) on …

Blast phase in chronic myelogenous leukemia is skewed toward unusual blast types in patients treated with tyrosine kinase inhibitors: a comparative study of 67 cases

Y Shi, AJ Rand, JH Crow, JO Moore… - American journal of …, 2015 - academic.oup.com
Objectives: To compare the features of the blast phase of chronic myelogenous leukemia
(CML) in patients treated with tyrosine kinase inhibitors (TKIs) with those in the pre-TKI era …

Megakaryocytic blast crisis as a presenting manifestation of chronic myeloid leukemia

ST Pullarkat, JW Vardiman, ML Slovak, DS Rao… - Leukemia Research, 2008 - Elsevier
Acute megakaryocytic leukemia is a rare form of acute myelogenous leukemia and may
occur either de novo or by transformation of a preexisting myelodysplastic or …

CD7 expression on CD34+ cells from chronic myeloid leukaemia in chronic phase

GA Martín‐Henao, R Quiroga… - American journal of …, 1999 - Wiley Online Library
Thirty‐seven patients with chronic phase chronic myeloid leukaemia and fourteen healthy
controls have been evaluated for lineage differentiation with immunological markers on …

Paraplegia as the presenting manifestation of extramedullary megakaryoblastic transformation of previously undiagnosed chronic myelogenous leukemia

BJ Bryant, JB Alperin… - American journal of …, 2007 - Wiley Online Library
Extramedullary tumors, also known as granulocytic sarcomas (GS), occur most frequently in
acute myelogenous leukemia (AML). They may signal the onset of the accelerated phase of …