Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells.
Invasion is a conserved process that relies on the timely and spatially controlled exocytosis …

The malaria parasite Plasmodium falciparum undergoes closed mitosis, which occurs within
an intact nuclear envelope, and differs significantly from its human host. Mitosis is …

Apicomplexan parasites secrete contents of the rhoptries, club-shaped organelles in the
apical region, into host cells to permit their invasion and establishment of infection. The …

Malaria remains a health and economic burden, particularly in marginalized populations
worldwide. The current strategies for combating malaria rely on eliminating the mosquito …

Malaria is a global and deadly human disease caused by the apicomplexan parasites of the
genus Plasmodium. Parasite proliferation within human red blood cells (RBCs) is associated …

Merozoite invasion of host red blood cells (RBCs) is essential for survival of the human
malaria parasite Plasmodium falciparum. Proteins involved with RBC binding and invasion …

Malaria is one of the serious health concerns worldwide as it remains a clinical challenge
due to the complex life cycle of the malaria parasite and the morphological changes it …

The human malaria parasite, Plasmodium falciparum, relies on Anopheles mosquitoes for
transmission. Once ingested during blood feeding, most parasites die in the mosquito …

Apicomplexan parasites secrete the contents of rhoptries into host cells to permit their
invasion and establishment of an infectious niche. The rhoptry secretory apparatus (RSA) …

A malária possui como agentes etiológicos os protozoários do gênero Plasmodium, sendo
que a espécie responsável pelos casos clínicos mais graves é o P. falciparum. Em 2021 …