Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …

Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …

As highlighted by recent genome-wide analyses in diverse organisms and cell types,
subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish …

Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

The eukaryotic family of RNA-binding proteins termed PUF (Pumilio and FBF) is known for
its roles in cell division, differentiation and development. The best-characterized function of …

Duplicated genes escape gene loss by conferring a dosage benefit or evolving diverged
functions. The yeast Saccharomyces cerevisiae contains many duplicated genes encoding …

Essentially all cells contain a variety of spatially restricted regions that are important for
carrying out specialized functions. Often, these regions contain specialized transcriptomes …

Translational control plays a major role in early development, differentiation and the cell
cycle. In this review, we focus on the four main mechanisms of translational control by 3 …

The asymmetric localization of mRNA plays an important role in coordinating
posttranscriptional events in eukaryotic cells. We investigated the peripheral mitochondrial …