Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Gold nanoparticles for in vitro diagnostics

W Zhou, X Gao, D Liu, X Chen - Chemical reviews, 2015 - ACS Publications
IVD test is a crucial component of clinical care that performs a diagnostic test on biological
samples that have been taken from a living body, such as blood, urine, and tissue.(1) Such …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Gold nanoparticles in chemical and biological sensing

K Saha, SS Agasti, C Kim, X Li, VM Rotello - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION Detection of chemical and biological agents plays a fundamental role in
biomedical, forensic and environmental sciences 1− 4 as well as in anti bioterrorism …

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

JE Dahlman, KJ Kauffman, Y Xing… - Proceedings of the …, 2017 - National Acad Sciences
Nucleic acid therapeutics are limited by inefficient delivery to target tissues and cells and by
an incomplete understanding of how nanoparticle structure affects biodistribution to off …

Single-layer transition metal dichalcogenide nanosheet-based nanosensors for rapid, sensitive, and multiplexed detection of DNA.

Y Zhang, B Zheng, C Zhu, X Zhang, C Tan… - … (Deerfield Beach, Fla …, 2014 - europepmc.org
Single-layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2,
are used as novel sensing platforms for sensitive and selective detection of DNA, based on …

Applications of nanoparticles in biology

M De, PS Ghosh, VM Rotello - Advanced Materials, 2008 - Wiley Online Library
The wide variety of core materials available, coupled with tunable surface properties, make
nanoparticles an excellent platform for a broad range of biological and biomedical …

Maximizing DNA loading on a range of gold nanoparticle sizes

SJ Hurst, AKR Lytton-Jean, CA Mirkin - Analytical chemistry, 2006 - ACS Publications
We have investigated the variables that influence DNA coverage on gold nanoparticles. The
effects of salt concentration, spacer composition, nanoparticle size, and degree of sonication …

Colorimetric detection of mercuric ion (Hg2+) in aqueous media using DNA-functionalized gold nanoparticles

JS Lee, MS Han, CA Mirkin - Angewandte Chemie-International …, 2007 - pure.korea.ac.kr
Color is everything: Hg 2+ in aqueous media is detected by the formation of thymidine-Hg 2+-
thymidine coordination complexes, which raises the melting temperature of the DNA …