Steroid sulfation and desulfation are fundamental pathways vital for a functional vertebrate
endocrine system. After biosynthesis, hydrophobic steroids are sulfated to expedite …

Steroids are small and highly important structural or signalling molecules in living organisms
and their metabolism is complex. Due to the multiplicity of enzymes involved there are many …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …

Liquid chromatography-mass spectrometry (LC-MS) is one of the most prominent analytical
techniques, due to its inherent selectivity and sensitivity. In LC-MS, chemical derivatizations …

Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable
tool for a wide range of applications. Matrix‐assisted laser desorption/ionization (MALDI) is …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …

Drug discovery and development is a high-risk, expensive endeavor and it commonly takes
about 10− 15 years to obtain marketing approval from project inception. 1 Research efforts …

High-spatial-resolution mass spectrometry imaging (HSR-MSI) provides precise spatial
information on thousands of biomolecules without labelling across a tissue section. Deep …

In the present study, we discuss the recent developments in oxysterol research. Exciting
results have been reported relating to the involvement of oxysterols in the fields of …

During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …