Introduction The activation of the kynurenine pathway in cancer progression and metastasis
through immunomodulatory pathways has drawn attention to the potential for kynurenine …

Despite considerable advances in the evolution of anticancer therapies, metastasis still
remains the main cause of cancer mortality. Therefore, current strategies for cancer cure …

CXC motif chemokine receptor 4 (CXCR4) is a promising therapeutic target of breast cancer
because it is overexpressed on cell surface of all molecular subtypes of breast cancer …

The metastatic behavior of melanoma has accentuated the need for specific therapy targets.
Compounds, namely l‐kynurenine (l‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) …

Background Cutaneous melanoma is a relentless form of cancer which continues to rise in
incidence. Currently, cutaneous melanoma is the leading cause of skin cancer‐related …

Chronic stress is a common cause of hair loss, involving inflammatory responses and
changes in cellular signaling pathways. This study explores the mechanism of action of the …

Melanoma, an invasive class of skin cancer, originates from mutations in melanocytes, the
pigment‐producing cells. Globally, approximately 132,000 new cases are reported each …

Melanoma is the third most common malignant skin tumor and has increased in morbidity
and mortality over the previous decade due to its rapid spread into the bloodstream or …

Introduction The inhibition of melanoma adhesion through adhesion molecules, such as
integrins and E-cadherin, may represent a promising strategy for managing melanoma …

CTCE‐9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4
phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and …