Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Cisplatin and other platinum compounds have had a huge impact in the treatment of cancers
and are applied in the majority of anticancer chemotherapeutic regimens. The success of …

Abstract Dr. Thomas Dougherty and his Oncology Foundation of Buffalo were the first to
support my (SOG) research into the effects of photodynamic therapy (PDT) on the host …

Photodynamic therapy (PDT) has the potential to make a significant impact on cancer
treatment. PDT can sensitize malignant tissues to light, leading to a highly selective effect if …

Photodynamic therapy (PDT) is a highly specific and clinically approved method for cancer
treatment in which a nontoxic drug known as photosensitizer (PS) is administered to a …

Photodynamic therapy (PDT) is a promising therapeutic modality for cancer treatment;
however, a more detailed understanding is needed to improve the clinical use of this …

Photodynamic therapy (PDT) was discovered over one hundred years ago when it was
observed that certain dyes could kill microorganisms when exposed to light in the presence …

Through the use of a rhodamine-appended chelate, bpy-Rho, a versatile strategy has been
demonstrated to readily form mitochondria-targeting photosensitizers via the incorporation of …

As a vital parameter in living cells and tissues, the micro-environment is crucial for the living
organisms. Significantly, organelles require proper micro-environment to achieve normal …

Photodynamic therapy (PDT) is a promising approach to treat head and neck cancer cells.
Here, we investigated whether mitochondrial iron uptake through mitoferrin-2 (Mfrn2) …