Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this
cytokine is a central player in immunity at the sites most exposed to microorganisms …

Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune
responses by secreting effector cytokines and regulating the functions of other innate and …

Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T
helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs) …

Reactive oxygen species (ROS) are generated by virus-infected cells; however, the
physiological importance of ROS generated under these conditions is unclear. Here we …

Abstract Interleukin-22 (IL-22) is a key effector molecule that is produced by activated T cells,
including T helper 22 (TH22) cells, TH17 cells and TH1 cells, as well as subsets of innate …

Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have
emerging roles in mediating immune responses and in regulating tissue homeostasis and …

Highlights•Th17 cells and cytokines are associated with the more severe phenotypes of
asthma.•IL-17A and IL-17F are associated with increased neutrophils in the airway.•IL-17A …

The classical model of immunity posits that the immune system reacts to pathogens and
injury and restores homeostasis. Indeed, a century of research has uncovered the means …

Pseudomonas aeruginosa is a complex gram-negative facultative anaerobe replete with a
variety of arsenals to activate, modify, and destroy host defense mechanisms. The microbe is …