Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer due to its highly
invasive nature that impedes the surgical removal of all tumor cells, making relapse …

Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …

Ovarian cancer is a highly metastatic disease and the leading cause of death from
gynecologic malignancy. Hence, and understanding of the molecular changes associated …

Epithelial–mesenchymal transition (EMT) is an important contributor to the invasion and
metastasis of epithelial-derived cancers. While considerable effort has focused in the …

During epithelial-mesenchymal transition (EMT) epithelial cancer cells transdifferentiate into
highly motile, invasive, mesenchymal-like cells, giving rise to disseminating tumor cells. Few …

Cancer is a pathology characterized by a loss or a perturbation of a number of typical
features of normal cell behaviour. Indeed, the acquisition of an inappropriate migratory and …

Fibronectin (FN) is a primary component of the mammary mesenchymal compartment and
undergoes dramatic changes during breast cancer development. Increased FN expression …

Abstract The microRNA-200 (miR-200) family restricts epithelial–mesenchymal transition
(EMT) and metastasis in tumor cell lines derived from mice that develop metastatic lung …

MIF is a proinflammatory cytokine and is implicated in cancer. A higher MIF level is found in
many human cancer and cancer‐prone inflammatory diseases, including chronic …