[HTML][HTML] SARS-CoV-2 VOCs, Mutational diversity and clinical outcome: Are they modulating drug efficacy by altered binding strength?
S Saifi, V Ravi, S Sharma, A Swaminathan… - Genomics, 2022 - Elsevier
The global COVID-19 pandemic continues due to emerging Severe Acute Respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC). Here, we performed …
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC). Here, we performed …
Biochemical characterization of emerging SARS-CoV-2 Nsp15 endoribonuclease variants
Global sequencing efforts from the ongoing COVID-19 pandemic, caused by the novel
coronavirus SARS-CoV-2, continue to provide insight into the evolution of the viral genome …
coronavirus SARS-CoV-2, continue to provide insight into the evolution of the viral genome …
[HTML][HTML] Unlocking the puzzle: non-defining mutations in SARS-CoV-2 proteome may affect vaccine effectiveness
E Ulzurrun, A Grande-Pérez, D Del Hoyo… - Frontiers in Public …, 2024 - frontiersin.org
Introduction SARS-CoV-2 variants are defined by specific genome-wide mutations
compared to the Wuhan genome. However, non-clade-defining mutations may also impact …
compared to the Wuhan genome. However, non-clade-defining mutations may also impact …
[HTML][HTML] Unraveling the genetic evolution of SARS-CoV-2 Recombinants using mutational dynamics across the different lineages
V Ravi, U Shamim, MA Khan, A Swaminathan… - Frontiers in …, 2024 - frontiersin.org
Introduction Recombination serves as a common strategy employed by RNA viruses for their
genetic evolution. Extensive genomic surveillance during the COVID-19 pandemic has …
genetic evolution. Extensive genomic surveillance during the COVID-19 pandemic has …
[HTML][HTML] In-depth genetic characterization of the SARS-CoV-2 pandemic in a two-year frame in North Macedonia using second and third generation sequencing …
M Vukovikj, G Boshevska, E Janchevska… - Frontiers in …, 2023 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a persistent
negative impact on both the public health and the global economy. To comprehend the …
negative impact on both the public health and the global economy. To comprehend the …