The research status, potential hazards and toxicological mechanisms of fluoroquinolone antibiotics in the environment

J Du, Q Liu, Y Pan, S Xu, H Li, J Tang - Antibiotics, 2023 - mdpi.com
Fluoroquinolone antibiotics are widely used in human and veterinary medicine and are
ubiquitous in the environment worldwide. This paper recapitulates the occurrence, fate, and …

BTEAC catalyzed ultrasonic-assisted synthesis of bromobenzofuran-oxadiazoles: Unravelling anti-HepG-2 cancer therapeutic potential through in vitro and in silico …

A Irfan, AF Zahoor, A Rasul, SA Al-Hussain… - International Journal of …, 2023 - mdpi.com
In this work, BTEAC (benzyl triethylammonium chloride) was employed as a phase transfer
catalyst in an improved synthesis (up to 88% yield) of S-alkylated bromobenzofuran …

Unfolding the antibacterial activity and acetylcholinesterase inhibition potential of benzofuran-triazole hybrids: Synthesis, antibacterial, acetylcholinesterase inhibition …

S Saeed, AF Zahoor, S Kamal, Z Raza, MA Bhat - Molecules, 2023 - mdpi.com
In this study, a series of novel benzofuran-based 1, 2, 4-triazole derivatives (10a–e) were
synthesized and evaluated for their inhibitory potential against acetylcholinesterase (AChE) …

Synthesis, Cytotoxic, and Computational Screening of Some Novel Indole–1,2,4-Triazole-Based S-Alkylated N-Aryl Acetamides

AF Zahoor, S Saeed, A Rasul, R Noreen, A Irfan… - Biomedicines, 2023 - mdpi.com
Molecular hybridization has emerged as the prime and most significant approach for the
development of novel anticancer chemotherapeutic agents for combating cancer. In this …

Acefylline Derivatives as a New Class of Anticancer Agents: Synthesis, Molecular Docking, and Anticancer, Hemolytic, and Thrombolytic Activities of Acefylline …

I Shahzadi, AF Zahoor, B Parveen, A Rasul… - Journal of …, 2022 - Wiley Online Library
The synthesis of novel acefyllines and exploring their biological activities attract researchers
due to their medicinal applications. Therefore, the current work reports the successful …

Synergistic biomedical potential and molecular docking analyses of coumarin–triazole hybrids as tyrosinase inhibitors: design, synthesis, in vitro profiling, and in silico …

R Kausar, AF Zahoor, H Tabassum, S Kamal… - Pharmaceuticals, 2024 - mdpi.com
The tyrosinase enzyme has a vital role in the browning of vegetables and fruits and the
biosynthesis of melanin. In this work, we synthesized a diverse library of coumarin–triazole …

Facile green approach towards the synthesis of some phenyl piperazine based dithiocarbamates as potent hemolytic and thrombolytic agents.

F Hafeez, A Mansha, AF Zahoor… - Pakistan Journal of …, 2021 - search.ebscohost.com
The facile and efficient protocol for the synthesis of N-phenyl piperazine based di-thio-
carbamates has been reported under neat conditions. A library of novel piperazine based di …

Facile one-pot approach to the synthesis of alkyl piperazine-1-carbodithioates as hemolytic and thrombolytic agents

F Hafeez, AF Zahoor, M Irfan, S Kamal… - Russian Journal of …, 2022 - Springer
A polyethylene glycol (PEG)-promoted methodology has been utilized for synthesis of
piperazine-based dithiocarbamates. One-pot reaction of N-methylpiperazine and N-Boc …

[PDF][PDF] Facile synthesis, antibacterial and protease inhibition studies of β-amino alcohols prepared via ring opening of epoxides.

R Noreen, H Aziz, F Hafeez, S Kamal… - Pakistan Journal of …, 2022 - researchgate.net
A green ultrasound assisted convenient approach has been reported for the ring opening of
epoxides. As a result, a series of N-phenyl piperazine and morpholine based β-amino …

Synthesis and α-glucosidase inhibition studies of norfloxacinacetanilide hybrids.

K Walayat, M Ahmad, UA Ashfaq… - Pakistan Journal of …, 2021 - search.ebscohost.com
Abstract α-Glucosidase inhibitors occupy a prominent position among the various treatments
of type-2 diabetes mellitus (DM2). In this study, a series of new norfloxacin-acetanilide …