Infectious complications, immune reconstitution, and infection prophylaxis after CD19 chimeric antigen receptor T-cell therapy

K Wudhikarn, MA Perales - Bone marrow transplantation, 2022 - nature.com
CD19-targeted chimeric antigen receptor (CAR) T-cell becomes a breakthrough therapy
providing excellent remission rates and durable disease control for patients with …

Immune control of cytomegalovirus reactivation in stem cell transplantation

MA Degli-Esposti, GR Hill - Blood, The Journal of the American …, 2022 - ashpublications.org
The reactivation of viruses from latency after allogeneic stem cell transplantation (SCT)
continues to represent a major clinical challenge requiring sophisticated monitoring …

Infections associated with CAR‐T cell therapy in patients with relapsed refractory multiple myeloma: Risks and prevention strategies

J An, J Zhao, P Zou, Y Zhang, J Wei, W Tian… - Cancer …, 2024 - Wiley Online Library
Background Chimeric antigen receptor T (CAR‐T) cell therapy has emerged as a potent
treatment for relapsed or refractory multiple myeloma, demonstrating significant clinical …

The role of allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia: A review

R Puckrin, M Shafey, J Storek - Frontiers in Oncology, 2023 - frontiersin.org
Although the use of allogeneic hematopoietic cell transplantation (HCT) for chronic
lymphocytic leukemia (CLL) has declined with the development of novel targeted agents, it …

Clinical outcomes of polyvalent immunoglobulin use in solid organ transplant recipients: A systematic review and meta‐analysis

S Bourassa‐Blanchette, GA Knoll, B Hutton… - Clinical …, 2019 - Wiley Online Library
Polyvalent immunoglobulin is commonly used for desensitization and treatment of antibody‐
mediated rejection in kidney transplantation but its impact on other outcomes is not known …

Prevention and management of human cytomegalovirus in pediatric HSCT recipients: A review

L Hiskey, T Madigan, EH Ristagno… - Frontiers in …, 2022 - frontiersin.org
Cytomegalovirus (CMV), like other herpesviruses, has the unique ability to establish latent
infection with subsequent reactivation during periods of stress and immunosuppression …

Controversies about immunoglobulin replacement therapy in HSCT recipients with hypogammaglobulinemia

A Ohmoto, S Fuji, KC Shultes, BN Savani… - Bone Marrow …, 2022 - nature.com
The efficacy of immunoglobulin replacement therapy (IgRT) has been demonstrated for
primary immune deficiency diseases and hematological malignancies such as chronic …

Management of humoral secondary immunodeficiency in hematological malignancies and following hematopoietic stem cell transplantation: Regional perspectives

MC Ar, R El Fakih, S Gabbassova, A Alhuraiji, F Nasr… - Leukemia Research, 2023 - Elsevier
Secondary immunodeficiency (SID) can occur as a result of multiple factors, including
hematological malignancies, hematopoietic stem cell transplantation (HSCT) …

[HTML][HTML] Immunoglobulin replacement to prevent infections in people with haematological malignancies and haematopoietic stem cell transplantation

KL Chai, EM Wood, LJ Estcourt, M Csenar… - The Cochrane …, 2024 - ncbi.nlm.nih.gov
Immunoglobulin replacement to prevent infections in people with haematological malignancies
and haematopoietic stem cell transplantation - PMC Back to Top Skip to main content NIH NLM …

[HTML][HTML] CMV management with specific immunoglobulins: a multicentric retrospective analysis on 92 allotransplanted patients

M Malagola, R Greco, S Santarone… - … of Hematology and …, 2019 - ncbi.nlm.nih.gov
CMV represents one of the most severe life-threatening complications of allogeneic stem
cell transplantation (allo-SCT). Pre-emptive treatment is highly effective, but toxicity and …