Cytomegalovirus diseases after hematopoietic stem cell transplantation: a mini-review

EJ Ariza-Heredia, L Nesher, RF Chemaly - Cancer letters, 2014 - Elsevier
Cytomegalovirus (CMV) infection remains a significant complication after hematopoietic
stem cell transplantation (HSCT) and may have a deleterious impact on the overall outcome …

Cytomegalovirus in solid organ transplantation: epidemiology, prevention, and treatment

E Beam, RR Razonable - Current infectious disease reports, 2012 - Springer
Cytomegalovirus (CMV) is one of the most important pathogens that infect solid organ
transplant recipients. CMV is associated with increased morbidity and mortality in this …

Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a …

O Manuel, S Husain, D Kumar, C Zayas… - Clinical infectious …, 2013 - academic.oup.com
Background. Cytomegalovirus (CMV) disease remains an important problem in solid-organ
transplant recipients, with the greatest risk among donor CMV-seropositive, recipient …

Harnessing anti-cytomegalovirus immunity for local immunotherapy against solid tumors

N Çuburu, L Bialkowski, SM Pontejo… - Proceedings of the …, 2022 - National Acad Sciences
Tumor infiltration by T cells profoundly affects cancer progression and responses to
immunotherapy. However, the tumor immunosuppressive microenvironment can impair the …

Clinical immune‐monitoring strategies for predicting infection risk in solid organ transplantation

M Fernández‐Ruiz, D Kumar… - Clinical & translational …, 2014 - Wiley Online Library
Infectious complications remain a leading cause of morbidity and mortality after solid organ
transplantation (SOT), and largely depend on the net state of immunosuppression achieved …

Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia

LF Lisboa, D Kumar, LE Wilson, A Humar - Transplantation, 2012 - journals.lww.com
Background. A CD8+ T-cell response to cytomegalovirus (CMV) has been associated with
control of viral replication. Assessment shortly after the onset of asymptomatic viremia could …

[HTML][HTML] Pretransplant interferon-γ secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation

S Cantisán, R Lara, M Montejo, J Redel… - American Journal of …, 2013 - Elsevier
In this prospective study we analyzed pretransplant interferon-γ secretion by
cytomegalovirus (CMV)-specific CD8+ T cells to assess its possible utility in determining the …

Identifying cytomegalovirus complications using the quantiferon-CMV assay after allogeneic hematopoietic stem cell transplantation

MK Yong, PU Cameron, M Slavin… - The Journal of …, 2017 - academic.oup.com
Background. A simple test to identify recovery of CMV-specific T-cell immunity following
hematopoietic stem cell transplantation (HSCT) could assist clinicians in managing CMV …

The ability of a cytomegalovirus ELISPOT assay to predict outcome of low-level CMV reactivation in hematopoietic cell transplant recipients

L El Haddad, E Ariza-Heredia, DP Shah… - The Journal of …, 2019 - academic.oup.com
Background Cytomegalovirus (CMV) infections in hematopoietic cell transplant (HCT)
recipients cause substantial morbidity and mortality. CMV cell-mediated immunity (CMV …

Absolute lymphocyte count: a predictor of recurrent cytomegalovirus disease in solid organ transplant recipients

BJ Gardiner, NE Nierenberg, JK Chow… - Clinical Infectious …, 2018 - academic.oup.com
Background Recurrent cytomegalovirus (CMV) disease in solid organ transplant recipients
frequently occurs despite effective antiviral therapy. We previously demonstrated that …