Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Single-cell approaches in human microbiome research
V Lloréns-Rico, JA Simcock, GRB Huys, J Raes - Cell, 2022 - cell.com
Microbial culturing and meta-omic profiling technologies have significantly advanced our
understanding of the taxonomic and functional variation of the human microbiome and its …
understanding of the taxonomic and functional variation of the human microbiome and its …
Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome
X Liu, X Tong, Y Zou, X Lin, H Zhao, L Tian, Z Jie… - Nature …, 2022 - nature.com
The gut microbiome has been implicated in a variety of physiological states, but controversy
over causality remains unresolved. Here, we performed bidirectional Mendelian …
over causality remains unresolved. Here, we performed bidirectional Mendelian …
A catalog of bacterial reference genomes from cultivated human oral bacteria
W Li, H Liang, X Lin, T Hu, Z Wu, W He… - npj Biofilms and …, 2023 - nature.com
The oral cavity harbors highly diverse communities of microorganisms. However, the
number of isolated species and high-quality genomes is limited. Here we present a …
number of isolated species and high-quality genomes is limited. Here we present a …
Metagenomics: An effective approach for exploring microbial diversity and functions
Various fields have been identified in the “omics” era, such as genomics, proteomics,
transcriptomics, metabolomics, phenomics, and metagenomics. Among these …
transcriptomics, metabolomics, phenomics, and metagenomics. Among these …
Identifying keystone species in microbial communities using deep learning
Previous studies suggested that microbial communities can harbour keystone species
whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an …
whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an …
Sex differences in the oral microbiome, host traits, and their causal relationships
The oral microbiome has been implicated in a growing number of diseases; however,
determinants of the oral microbiome and their roles remain elusive. Here, we investigated …
determinants of the oral microbiome and their roles remain elusive. Here, we investigated …
Mendelian randomization analyses reveal causal relationships between the human microbiome and longevity
Although recent studies have revealed the association between the human microbiome
especially gut microbiota and longevity, their causality remains unclear. Here, we assess the …
especially gut microbiota and longevity, their causality remains unclear. Here, we assess the …
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome
X Liu, X Tong, J Zhu, L Tian, Z Jie, Y Zou, X Lin… - Cell discovery, 2021 - nature.com
The oral microbiota contains billions of microbial cells, which could contribute to diseases in
many body sites. Challenged by eating, drinking, and dental hygiene on a daily basis, the …
many body sites. Challenged by eating, drinking, and dental hygiene on a daily basis, the …
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring
The impact of gestational diabetes mellitus (GDM) on maternal or infant microbiome
trajectory remains poorly understood. Utilizing large-scale longitudinal fecal samples from …
trajectory remains poorly understood. Utilizing large-scale longitudinal fecal samples from …