Estrogen receptors regulate innate immune cells and signaling pathways

S Kovats - Cellular immunology, 2015 - Elsevier
Humans show strong sex differences in immunity to infection and autoimmunity, suggesting
sex hormones modulate immune responses. Indeed, receptors for estrogens (ERs) regulate …

Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis

DP Robinson, SL Klein - Hormones and behavior, 2012 - Elsevier
This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.”
During pregnancy, it is evolutionarily advantageous for inflammatory immune responses that …

The Xs and Y of immune responses to viral vaccines

SL Klein, A Jedlicka, A Pekosz - The Lancet infectious diseases, 2010 - thelancet.com
The biological differences associated with the sex of an individual are a major source of
variation, affecting immune responses to vaccination. Compelling clinical data illustrate that …

Immune cells have sex and so should journal articles

SL Klein - Endocrinology, 2012 - academic.oup.com
Males and females have the same immunological cells, proteins, and pathways in place to
protect against the development of disease. The kinetics, magnitude, and skewing of the …

17β-Estradiol, a potential ally to alleviate SARS-CoV-2 infection

AC Breithaupt-Faloppa, CJ Correia, CM Prado… - Clinics, 2020 - SciELO Brasil
Considering that female sexual hormones may modulate the inflammatory response and
also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the …

Estrogen receptors regulate an inflammatory pathway of dendritic cell differentiation: mechanisms and implications for immunity

S Kovats - Hormones and behavior, 2012 - Elsevier
This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.”
Immune cells and hematopoietic progenitors express estrogen receptors (ER). As ligand …

[HTML][HTML] Dendritic cells from the human female reproductive tract rapidly capture and respond to HIV

M Rodriguez-Garcia, Z Shen, FD Barr, AW Boesch… - Mucosal …, 2017 - Elsevier
Dendritic cells (DCs) throughout the female reproductive tract (FRT) were examined for
phenotype, HIV capture ability and innate anti-HIV responses. Two main CD11c+ DC …

Fetal programming of schizophrenia: select mechanisms

M Debnath, G Venkatasubramanian, M Berk - … & Biobehavioral Reviews, 2015 - Elsevier
Mounting evidence indicates that schizophrenia is associated with adverse intrauterine
experiences. An adverse or suboptimal fetal environment can cause irreversible changes in …

Immunogenicity of an inactivated monovalent 2009 H1N1 influenza vaccine in pregnant women

LA Jackson, SM Patel, GK Swamy… - Journal of Infectious …, 2011 - academic.oup.com
Background. Although pregnant women are at increased risk of severe illness following
influenza infection, there is relatively little information on the immunogenicity of influenza …

Estradiol Reduces Susceptibility of CD4+ T Cells and Macrophages to HIV-Infection

M Rodriguez-Garcia, N Biswas, MV Patel, FD Barr… - PloS one, 2013 - journals.plos.org
The magnitude of the HIV epidemic in women requires urgent efforts to find effective
preventive methods. Even though sex hormones have been described to influence HIV …