Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate

L Bonello, US Tantry, R Marcucci, R Blindt… - Journal of the American …, 2010 - jacc.org
The addition of clopidogrel to aspirin treatment reduces ischemic events in a wide range of
patients with cardiovascular disease. However, recurrent ischemic event occurrence during …

ACCF/AHA clopidogrel clinical alert: approaches to the FDA “Boxed Warning” a report of the american college of cardiology foundation task force on clinical expert …

Writing Committee Members, DR Holmes Jr… - Circulation, 2010 - Am Heart Assoc
ciation (AHA) convened a writing committee. The ACCF and AHA adhere to a rigorous policy
regarding relationships with industry and other entities (RWI) of authors and peer reviewers …

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic …

L Wallentin, S James, RF Storey, M Armstrong… - The Lancet, 2010 - thelancet.com
Background In the PLATO trial of ticagrelor versus clopidogrel for treatment of acute
coronary syndromes, ticagrelor reduced the composite outcome of cardiovascular death …

Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: Design and rationale for the Effective aNticoaGulation …

CT Ruff, RP Giugliano, EM Antman, SE Crugnale… - American heart …, 2010 - Elsevier
BACKGROUND: Vitamin K antagonists have been the standard oral antithrombotic used for
more than a half century for prevention and treatment of thromboembolism. Their limitations …

Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants

S Sayols-Baixeras, C Lluís-Ganella… - The application of …, 2014 - Taylor & Francis
Coronary artery disease (CAD) is the leading cause of death and disability worldwide, and
its prevalence is expected to increase in the coming years. CAD events are caused by the …

Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis

G Cayla, JS Hulot, SA O'Connor, A Pathak, SA Scott… - Jama, 2011 - jamanetwork.com
Context Despite dual antiplatelet therapy, stent thrombosis remains a devastating and
unpredictable complication of percutaneous coronary intervention (PCI). Objective To …

Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatments

D Della-Morte, F Guadagni, R Palmirotta… - …, 2012 - Taylor & Francis
Stroke remains a leading cause of death worldwide and the first cause of disability in the
western world. Ischemic stroke (IS) accounts for almost 80% of the total cases of strokes and …

Antithrombotic therapy in patients with chronic kidney disease

D Capodanno, DJ Angiolillo - Circulation, 2012 - Am Heart Assoc
Chronic kidney disease (CKD) is a pandemic public health problem, with 500 million people
worldwide estimated to have some form of kidney injury. 1 Survey data suggest that the …

Antithrombotic therapy in the elderly

D Capodanno, DJ Angiolillo - Journal of the American College of …, 2010 - jacc.org
Antithrombotic therapy represents the mainstay of treatment for prevention of recurrent
ischemic events in patients with atherothrombotic disease processes. Although the benefits …

ABCD‐GENE score and clinical outcomes following percutaneous coronary intervention: insights from the TAILOR‐PCI trial

D Capodanno, DJ Angiolillo, RJ Lennon… - Journal of the …, 2022 - Am Heart Assoc
Background In TAILOR‐PCI, genotype‐guided selection of P2Y12 inhibitors after
percutaneous coronary intervention did not significantly reduce the risk of ischemic events at …