Multiplex Ligation-dependent Probe Amplification (MLPA) assay is a recently developed
technique able to evidence variations in the copy number of several human genes. Due to …

Treatment of childhood acute lymphoblastic leukaemia (ALL) has improved considerably in
recent years. A contributing factor has been the improved stratification for treatment …

We revisited the prognostic value of frequently detected somatic gene copy number
alterations (CNAs) in mantle cell lymphoma (MCL) patients treated first line with …

Recent genomic studies have shown that copy number abnormalities (CNA) of genes
involved in lymphoid differentiation and cell cycle control are common in B‐cell precursor …

Aminoimidazole-4-carboxamide riboside or acadesine (AICAR) induces apoptosis in
chronic lymphocytic leukemia (CLL) cells. A clinical study of AICAR is currently being …

We studied a series of spindle cell lipomas arising in atypical sites and showing unusual
morphologic features (which we called atypical spindle cell lipoma) to assess if these …

Recurrent and clonal genetic alterations are characteristic of different subtypes of T-and B-
cell lymphoblastic leukemia (ALL), and several subtypes are strong independent predictors …

Risk stratification in myeloma requires an accurate assessment of the presence of a range of
molecular abnormalities including the differing IGH translocations and the recurrent copy …

Genomic characterization is an essential part of the clinical management of hematological
malignancies for diagnostic, prognostic and therapeutic purposes. Although CBA and FISH …

Background Banding-karyotyping and metaphase-directed-fluorescence-in-situhybridization
(FISH) may be hampered by low mitotic index in leukemia. Interphase FISH (iFISH) is a way …