Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …

Ryanodine receptors (RyRs) are located in the sarcoplasmic/endoplasmic reticulum
membrane and are responsible for the release of Ca2+ from intracellular stores during …

Ryanodine receptors (RyRs) are a distinct class of ligand-gated calcium channels
controlling the release of calcium from intracellular stores. They are located on the …

The endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) form major intracellular
Ca 2+ stores. Ryanodine receptors (RyRs) are large tetrameric ion channels in the SR and …

The ryanodine receptors (RyRs) are intracellular calcium channels responsible for rapid
release of Ca 2+ from the sarcoplasmic/endoplasmic reticulum (SR/ER) to the cytoplasm …

It has been six years since the first reported link between mutations in the cardiac ryanodine
receptor Ca2+ release channel (RyR2) and catecholaminergic polymorphic ventricular …

RyRs are large homotetrameric proteins that are∼ 4/5 cytoplasmic and∼ 1/5
transmembrane and luminal in mass. Mutations in RyRs produce human disease and many …

Ryanodine receptors (RyRs) are huge homotetrameric Ca 2+ release channels localized to
the sarcoplasmic reticulum. RyRs are responsible for the release of Ca 2+ from the SR …

The flow of intracellular calcium (Ca2+) is critical for the activation and regulation of
important biological events that are required in living organisms. As the major Ca2+ …

Ryanodine receptors (RyRs) form channels responsible for the release of Ca2+ from the
endoplasmic and sarcoplasmic reticulum. The SPRY2 domain in the skeletal muscle isoform …