Trehalose is a natural disaccharide synthesized in various life forms, but not found in
vertebrates. An increasing body of evidence demonstrates exceptional bioprotective …

Spinal cord injury (SCI) leaves a temporary or enduring motor, sensory, and autonomic
function loss, significantly impacting the patient's quality of life. Given their biocompatibility …

Abstract Background Traumatic Brain Injury (TBI) present a significant burden to global
health. Close association and mutual regulation exist between the brain and gut microbiota …

Addiction is a pressing social problem worldwide and opioid dependence can be
considered the strongest and most difficult addiction to treat. Mesolimbic and mesocortical …

After intracerebral hemorrhage (ICH), brain edema commonly occurs and can cause death.
Along with edema, there are significant alterations in the concentrations of key ions such as …

Trehalose is a naturally occurring disaccharide that has recently gained significant attention
for its neuroprotective properties in various models of neurodegeneration. This review …

Abstract Zinc (Zn (II)) is a divalent cation involved in regulating intracellular signal
transduction and gene expression through transcription factor activity, and can act as a …

Spinal cord injury (SCI) can cause very serious bodily harm or even paralysis. However, all
clinical drugs require long-term use to relieve the disease, causing toxicity and side effects …

Background TBI is a major global health issue due to its high morbidity and mortality rates.
Persistent neurodegeneration following secondary brain injuries is a significant concern …

The essential trace metals iron, zinc, and copper have a significant physiological role in
healthy brain development and function. Especially zinc is important for neurogenesis …