From molecules to behavior: Implications for perineuronal net remodeling in learning and memory
B Sanchez, P Kraszewski, S Lee… - Journal of …, 2024 - Wiley Online Library
Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) structures found
throughout the central nervous system that regulate plasticity. They consist of a …
throughout the central nervous system that regulate plasticity. They consist of a …
Perineuronal nets: subtle structures with large implications
H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system …
the soma and proximal dendrites of certain neurons in the central nervous system …
A comprehensive atlas of perineuronal net distribution and colocalization with parvalbumin in the adult mouse brain
Perineuronal nets (PNNs) surround specific neurons in the brain and are involved in various
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …
forms of plasticity and clinical conditions. However, our understanding of the PNN role in …
[HTML][HTML] Phagocytosis of aggrecan-positive perineuronal nets surrounding motor neurons by reactive microglia expressing MMP-9 in TDP-43Q331K ALS model mice
SW Cheung, EF Willis, DG Simmons… - Neurobiology of …, 2024 - Elsevier
Perineuronal nets (PNNs) are extracellular matrix structures that surround excitable neurons
and their proximal dendrites. PNNs play an important role in neuroprotection against …
and their proximal dendrites. PNNs play an important role in neuroprotection against …
Fine structure analysis of perineuronal nets in the ketamine model of schizophrenia
R Kaushik, N Lipachev, G Matuszko… - European Journal of …, 2021 - Wiley Online Library
Perineuronal nets (PNNs) represent a highly condensed specialized form of brain
extracellular matrix (ECM) enwrapping mostly parvalbumin‐positive interneurons in the …
extracellular matrix (ECM) enwrapping mostly parvalbumin‐positive interneurons in the …
Multiple particle tracking detects changes in brain extracellular matrix and predicts neurodevelopmental age
M McKenna, D Shackelford, H Ferreira Pontes, B Ball… - ACS …, 2021 - ACS Publications
Brain extracellular matrix (ECM) structure mediates many aspects of neural development
and function. Probing structural changes in brain ECM could thus provide insights into …
and function. Probing structural changes in brain ECM could thus provide insights into …
Recovery of Forearm and fine digit function after chronic spinal cord Injury by Simultaneous Blockade of Inhibitory Matrix Chondroitin Sulfate Proteoglycan Production …
AJ Milton, JCF Kwok, J McClellan, SG Randall… - Journal of …, 2023 - liebertpub.com
Spinal cord injuries (SCI), for which there are limited effective treatments, result in enduring
paralysis and hypoesthesia, in part because of the inhibitory microenvironment that …
paralysis and hypoesthesia, in part because of the inhibitory microenvironment that …
Proteoglycans and glycosaminoglycans in central nervous system injury
N Siddiqui, K Oshima… - American Journal of …, 2022 - journals.physiology.org
The brain and spinal cord constitute the central nervous system (CNS), which when injured,
can be exceedingly devastating. The mechanistic roles of proteoglycans (PGs) and their …
can be exceedingly devastating. The mechanistic roles of proteoglycans (PGs) and their …
The tetrapartite synapse in neuropsychiatric disorders: Matrix metalloproteinases (MMPs) as promising targets for treatment and rational drug design
AJM Chaves Filho, M Mottin, DB Lós, CH Andrade… - Biochimie, 2022 - Elsevier
Inflammation and an exacerbated immune response are widely accepted contributing
mechanisms to the genesis and progression of major neuropsychiatric disorders. However …
mechanisms to the genesis and progression of major neuropsychiatric disorders. However …
Postnatal fluoxetine treatment alters perineuronal net formation and maintenance in the hippocampus
S Mukhopadhyay, A Chatterjee, P Tiwari, U Ghai… - ENeuro, 2021 - eneuro.org
Elevation of serotonin via postnatal fluoxetine (PNFlx) treatment during critical temporal
windows is hypothesized to perturb the development of limbic circuits thus establishing a …
windows is hypothesized to perturb the development of limbic circuits thus establishing a …