Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

In the wake of the success of modern immunotherapy, oncolytic viruses (OVs) are currently
seen as a potential therapeutic option for patients with cancer who do not respond or fail to …

Oncolytic viruses (OVs) represent a new class of multi-modal immunotherapies for cancer,
with OV-elicited antitumor immunity being key to their overall therapeutic efficacy. Currently …

Oncolytic viruses represent a new class of therapeutic agents that promote anti-tumour
responses through a dual mechanism of action that is dependent on selective tumour cell …

Oncolytic viruses (OVs) constitute a new and promising immunotherapeutic approach
toward cancer treatment. This therapy takes advantage of the natural propensity of most …

Aging is a major risk factor for many diseases including metabolic syndrome, cancer,
inflammation, and neurodegeneration. Identifying mechanistic common denominators …

Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor
of the central nervous system and has a very poor prognosis. The current standard of care …

Viral infections are initiated by attachment of the virus to host cell surface receptors,
including sialic acid-containing glycans. It is now possible to rapidly identify specific glycan …

Many mammalian viruses have properties that can be commandeered for the treatment of
cancer. These characteristics include preferential infection and replication in tumor cells, the …

Oncolytic viruses are native or engineered viruses that preferentially replicate in and lyse
cancer cells. Selective tumor cell replication is thought to depend on infection of neoplastic …