Manganese‐enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations

AC Silva, JH Lee, I Aoki… - NMR in Biomedicine: An …, 2004 - Wiley Online Library
Manganese‐enhanced MRI (MEMRI) is being increasingly used for MRI in animals due to
the unique T1 contrast that is sensitive to a number of biological processes. Three specific …

Blood supply and vascular reactivity of the spinal cord under normal and pathological conditions: A review

NL Martirosyan, JS Feuerstein, N Theodore… - … of Neurosurgery: Spine, 2011 - thejns.org
The authors present a review of spinal cord blood supply, discussing the anatomy of the
vascular system and physiological aspects of blood flow regulation in normal and injured …

Neuronal activity rapidly induces transcription of the CREB‐regulated microRNA‐132, in vivo

AS Nudelman, DP DiRocco, TJ Lambert… - …, 2010 - Wiley Online Library
Activity‐dependent changes in gene‐expression are believed to underlie the molecular
representation of memory. In this study, we report that in vivo activation of neurons rapidly …

MRI contrast agents: current status and future perspectives

GJ Strijkers, WJ M Mulder… - Anti-Cancer Agents …, 2007 - ingentaconnect.com
Magnetic Resonance Imaging (MRI) is increasingly used in clinical diagnostics, for a rapidly
growing number of indications. The MRI technique is non-invasive and can provide …

Cellular MR imaging

M Modo, M Hoehn, JWM Bulte - Molecular imaging, 2005 - journals.sagepub.com
Cellular MR imaging is a young field that aims to visualize targeted cells in living organisms.
In order to provide a different signal intensity of the targeted cell, they are either labeled with …

Manganese neurotoxicity: a focus on the neonate

KM Erikson, K Thompson, J Aschner… - Pharmacology & …, 2007 - Elsevier
Manganese (Mn) is an essential trace metal found in all tissues, and it is required for normal
amino acid, lipid, protein, and carbohydrate metabolism. While Mn deficiency is extremely …

In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI

I Aoki, YJL Wu, AC Silva, RM Lynch, AP Koretsky - Neuroimage, 2004 - Elsevier
Visualizing brain anatomy in vivo could provide insight into normal and pathophysiology.
Here it is demonstrated that neuroarchitecture can be detected in the rodent brain using MRI …

In vivo auditory brain mapping in mice with Mn-enhanced MRI

X Yu, YZ Wadghiri, DH Sanes, DH Turnbull - Nature neuroscience, 2005 - nature.com
There are currently no noninvasive imaging methods available for auditory brain mapping in
mice, despite the increasing use of genetically engineered mice to study auditory brain …

Influence of iron metabolism on manganese transport and toxicity

Q Ye, JE Park, K Gugnani, S Betharia… - Metallomics, 2017 - academic.oup.com
Although manganese (Mn) is critical for the proper functioning of various metabolic enzymes
and cofactors, excess Mn in the brain causes neurotoxicity. While the exact transport …

Manganese‐enhanced magnetic resonance imaging (MEMRI)

AP Koretsky, AC Silva - … An International Journal Devoted to the …, 2004 - Wiley Online Library
Abstract Manganese ion (Mn2+) is an essential metal that participates as a cofactor in a
number of critical biological functions, such as electron transport, detoxification of free …