[HTML][HTML] Regulation of the Lewis blood group antigen expression: a literature review supplemented with computational analysis

M Wipplinger, S Mink, M Bublitz… - Transfusion Medicine and …, 2024 - karger.com
Background: The Lewis (Le) blood group system, unlike most other blood groups, is not
defined by antigens produced internally to the erythrocytes and their precursors but rather by …

[HTML][HTML] Regulation of Blood Group Expression: Another Layer of Complexity to Consider

C Gassner, ML Olsson - Transfusion Medicine and Hemotherapy, 2024 - karger.com
The genetic code of the DNA sequences and their polymorphisms in coding regions of blood
group genes essentially explain the general variation in blood group phenotypes observed …

Epigenetic dissection of human blood group genes reveals regulatory elements and detailed characteristics of KEL and four other loci

PC Wu, EC McGowan, YQ Lee, S Ghosh… - …, 2024 - Wiley Online Library
Background Blood typing is essential for safe transfusions and is performed serologically or
genetically. Genotyping predominantly focuses on coding regions, but non‐coding variants …

Clinical significance of decreased or loss of ABO blood group expression in acute myeloid leukaemia: A single‐centre retrospective study

JH Han, H Lee, JK Kim, J Yoo, K Park… - Vox …, 2024 - Wiley Online Library
Abstract Background and Objectives Decreased or loss of ABO blood group antigen
expression has been observed in acute myeloid leukaemia (AML) patients. We studied the …

[PDF][PDF] A Bioinformatically Initiated Approach to Evaluate GATA1 Regulatory Regions in Samples with Weak D, Del, or D-Phenotypes Despite Normal RHD Exons

EC McGowan, PC Wu, Å Hellberg… - Transfusion …, 2024 - research.usc.edu.au
Introduction: With over 360 blood group antigens in systems recognized, there are antigens,
such as RhD, which demonstrate a quantitative reduction in antigen expression due to …

A Bioinformatically Initiated Approach to Evaluate GATA1 Regulatory Regions in Samples with Weak D, Del, or D–Phenotypes Despite Normal RHD Exons

ECMGPC Wua, ÅHGH Lopezc, CA Hylandc… - 2024 - karger.com
Introduction: With over 360 blood group antigens in systems recognized, there are antigens,
such as RhD, which demonstrate a quantitative reduction in antigen expression due to …

[HTML][HTML] Epigenetic Dissection of Human Blood Group Genes Reveals Unknown Regulatory Elements and Detailed Characteristics of KEL and Other Loci

PC Wu, E McGowan, YQ Lee, S Ghosh, J Hansson… - Blood, 2023 - Elsevier
Accurate blood group typing is essential for compatible blood transfusions and can often be
achieved with the combination of serology and genotyping technologies. Currently, most …