Management of frailty: opportunities, challenges, and future directions

E Dent, FC Martin, H Bergman, J Woo… - The Lancet, 2019 - thelancet.com
Frailty is a complex age-related clinical condition characterised by a decline in physiological
capacity across several organ systems, with a resultant increased susceptibility to stressors …

A systematic review of the evidence for deprescribing interventions among older people living with frailty

K Ibrahim, NJ Cox, JM Stevenson, S Lim, SDS Fraser… - BMC geriatrics, 2021 - Springer
Background Older people living with frailty are often exposed to polypharmacy and potential
harm from medications. Targeted deprescribing in this population represents an important …

Physical frailty: ICFSR international clinical practice guidelines for identification and management

E Dent, JE Morley, AJ Cruz-Jentoft… - The journal of nutrition …, 2019 - Springer
Objective The task force of the International Conference of Frailty and Sarcopenia Research
(ICFSR) developed these clinical practice guidelines to overview the current evidence-base …

Polypharmacy in elderly people

P Dovjak - Wiener Medizinische Wochenschrift, 2022 - Springer
Polypharmacy characterizes ongoing prescription of multiple medications in a patient.
Following the demographic change and growing number of elderly patients, polypharmacy …

[HTML][HTML] Recent developments in frailty identification, management, risk factors and prevention: A narrative review of leading journals in geriatrics and gerontology

E Dent, P Hanlon, M Sim, J Jylhävä, Z Liu… - Ageing Research …, 2023 - Elsevier
Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis

E Radcliffe, R Servin, N Cox, S Lim, QY Tan, C Howard… - BMC geriatrics, 2023 - Springer
Background A third of older people take five or more regular medications (polypharmacy).
Conducting medication reviews in primary care is key to identify and reduce/stop …

Deprescribing tools: a review of the types of tools available to aid deprescribing in clinical practice

E Reeve - Journal of pharmacy practice and research, 2020 - Wiley Online Library
The importance of deprescribing, which is the process of withdrawing an inappropriate
medication, supervised by a healthcare professional with the goal of managing …

The double burden of the COVID-19 pandemic and polypharmacy on geriatric population–public health implications

S Rahman, K Singh, S Dhingra, J Charan… - … and clinical risk …, 2020 - Taylor & Francis
COVID-19 pandemic is inducing acute respiratory distress syndrome, multi-organ failure,
and eventual death. Respiratory failure is the leading cause of mortality in the elderly …

Depression, antidepressants and fall risk: therapeutic dilemmas—a clinical review

EP Van Poelgeest, AC Pronk, D Rhebergen… - European geriatric …, 2021 - Springer
Purpose The aim of this clinical review was to summarize the existing knowledge on fall risk
associated with antidepressant use in older adults, describe underlying mechanisms, and …

[HTML][HTML] Deprescribing in older people

M Liacos, AT Page, C Etherton-Beer - Australian prescriber, 2020 - ncbi.nlm.nih.gov
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