The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

For decades, it was commonly accepted that the brain is secluded from peripheral immune
activity and is self-sufficient for its maintenance and repair. This simplistic perception was …

The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …

The nervous and immune systems are intricately linked. Although psychological stress is
known to modulate immune function, mechanistic pathways linking stress networks in the …

Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

Immune cells are being engineered to recognize and respond to disease states, acting as a
“living drug” when transferred into patients. Therapies based on engineered immune cells …

Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Metastasis is initiated and sustained through therapy by cancer cells with stem-like and
immune-evasive properties, termed metastasis-initiating cells (MIC). Recent progress …

The blood circulation is considered the only way for the orally administered nanoparticles to
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …

Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …