Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

[HTML][HTML] The role of glutathione in prevention of COVID-19 immunothrombosis: a review

I Glassman, N Le, M Mirhosseini… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Immunothrombosis has emerged as a dominant pathological process exacerbating
morbidity and mortality in acute-and long-COVID-19 infections. The hypercoagulable state is …

A swellable hydrogel microneedle based on cerium-metal organic frame composite nanozyme for detection of biomarkers

J Zhao, J Lv, G Ling, P Zhang - International Journal of Biological …, 2024 - Elsevier
Skin interstitial fluid (ISF) has been an alternative source in the field of biomarkers analysis.
This work developed swellable hydrogel microneedles (MNs) composed of polyvinyl alcohol …

Glutathione modulates efficacious changes in the immune response against tuberculosis

A Abnousian, J Vasquez, K Sasaninia, M Kelley… - Biomedicines, 2023 - mdpi.com
Glutathione (GSH) is an antioxidant in human cells that is utilized to prevent damage
occurred by reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy …

Glutathione and glutathione disulfide–their biomedical and pharmaceutical applications

X Guan - Medicinal Chemistry Research, 2023 - Springer
Glutathione (GSH) is an endogenous tripeptide (Glu-Cys-Gly) and the most abundant
endogenous antioxidant. It protects the body against oxidative stress and reactive …

Modulating macrophage function to reinforce host innate resistance against Mycobacterium avium complex infection

HE Park, W Lee, S Choi, M Jung, MK Shin… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Role of Oxidative Stress in Tuberculosis Meningitis Infection in Diabetics

I Navasardyan, S Yeganyan, H Nguyen, P Vaghashia… - Biomedicines, 2023 - mdpi.com
Tuberculosis meningitis (TBM) is a result of the invasion of the meninges with the bacilli of
Mycobacterium tuberculosis (Mtb), leading to inflammation of the meninges around the brain …

Topical Absorption of Glutathione–Cyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium …

K Sasaninia, M Kelley, A Abnousian, A Badaoui… - Antioxidants, 2023 - mdpi.com
Glutathione (GSH) is an important intracellular antioxidant responsible for neutralizing
reactive oxygen species (ROS). Our laboratory previously demonstrated that the oral …

L-GSH Supplementation in Conjunction With Rifampicin Augments the Treatment Response to Mycobacterium tuberculosis in a Diabetic Mouse Model

A Beever, N Kachour, J Owens, K Sasaninia… - Frontiers in …, 2022 - frontiersin.org
Both active tuberculosis (TB) and asymptomatic latent Mycobacterium tuberculosis (M. tb)
infection (LTBI) cause significant health burdens to humans worldwide. Individuals with …

Liposomal Glutathione Helps to Mitigate Mycobacterium tuberculosis Infection in the Lungs

N Kachour, A Beever, J Owens, R Cao, A Kolloli… - Antioxidants, 2022 - mdpi.com
Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is responsible
for causing significant morbidity and mortality, especially among individuals with …