Cardiac fibrosis remains an important health concern, but the study of fibroblast biology has
been hindered by a lack of effective means for identifying and tracking fibroblasts. Recent …

The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

The new type of pneumonia caused by the SARS-CoV-2 (Severe acute respiratory
syndrome coronavirus 2) has been declared as a global public health concern by WHO. As …

Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …

The placenta is a gender-specific transitory organ with the sole purpose of enabling the
growth and development of the fetus. It mediates the efficient transfer and exchange of …

The superfamily of tumor necrosis factor (TNF) receptors includes osteoprotegerin (OPG)
and its ligands, which are receptor activators of nuclear factor kappa-B ligand (RANKL) and …

Diseases that jeopardize the musculoskeletal system and cause chronic impairment are
prevalent throughout the Western world. In Germany alone,~ 1.8 million patients suffer from …

For the past decades, heart diseases remain the leading cause of death worldwide. In the
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …

Piezo1 forms mechanically activated nonselective cation channels that contribute to
endothelial response to fluid flow. Here we reveal an important role in the control of capillary …

Skeletal muscle wasting, whether related to physiological ageing, muscle disuse or to an
underlying chronic disease, is a key determinant to quality of life and mortality. However …