Praziquantel

D Cioli, L Pica-Mattoccia - Parasitology research, 2003 - Springer
Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. This
review summarizes the main features of the drug, with special attention being given to those …

Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental …

G Zdesenko, F Mutapi - PLoS neglected tropical diseases, 2020 - journals.plos.org
Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …

Pharmacokinetic optimisation of the treatment of neurocysticercosis

J Sotelo, H Jung - Clinical pharmacokinetics, 1998 - Springer
Neurocysticercosis is the most important parasitic infection of the nervous system. It is
common in communities living in conditions with poor hygiene. Until the last 2 decades …

Formulation, characterization and pharmacokinetics of praziquantel-loaded hydrogenated castor oil solid lipid nanoparticles

S Xie, B Pan, M Wang, L Zhu, F Wang, Z Dong… - …, 2010 - Taylor & Francis
Aim: The purpose of this study was to formulate praziquantel (PZQ)-loaded hydrogenated
castor oil (HCO) solid lipid nanoparticles (SLN) to enhance the bioavailability and prolong …

Pharmacokinetic study of praziquantel administered alone and in combination with cimetidine in a single-day therapeutic regimen

H Jung, R Medina, N Castro, T Corona… - Antimicrobial agents …, 1997 - Am Soc Microbiol
A brief therapeutic regimen of praziquantel, reduced to a single day, has been effective for
treatment of neurocysticercosis. To study its pharmacokinetic characteristics, levels of …

Medical treatment for neurocysticercosis: drugs, indications and perspectives

A Fleury, H Jung, G Cardenas… - Current topics in …, 2008 - ingentaconnect.com
Neurocysticercosis is one of the most frequent parasitic diseases affecting the central
nervous system. The introduction of anticysticidal therapy in the early 80's and the …

Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge

AR Said, HS Zoghroban, MF Arafa… - Drug Development …, 2021 - Taylor & Francis
WHO considers praziquantel (PZQ) as the drug of choice for treatment of Schistosoma
mansoni infection but this requires high dose due to poor solubility and first pass …

Treatment of Microcotyle sebastis infestation in cultured rockfish Sebastes schlegeli by oral administration of praziquantel in combination with cimetidine

KH Kim, EH Lee, SR Kwon, JB Cho - Diseases of aquatic organisms, 2001 - int-res.com
The effect of cimetidine on the treatment efficacy of praziquantel against Microcotyle sebastis
infestation in cultured rockfish Sebastes schlegeli was investigated. Juvenile rockfish were …

Cimetidine enhances the plasma praziquantel concentration and treatment efficacy against Microcotyle sebastis in cultured rockfish Sebastes schlegeli

KH Kim, CS Kim - Diseases of aquatic organisms, 2002 - int-res.com
The effect of cimetidine on the praziquantel concentration in the blood of the rockfish
Sebastes schlegeli and the consequent effect on the treatment efficacy against Microcotyle …

[PDF][PDF] Efficacy of praziquantel for the treatment of schistosomiasis in Ethiopia

K Deribew, B Petros - Int J Med Med Sci, 2013 - academicjournals.org
Schistosomiasis is a tropical disease caused by blood-dwelling fluke of the genus
Schistosoma. The main schistosomes infecting human beings are: Schistosoma mansoni …