[HTML][HTML] Necroptosis: a new target for prevention of osteoporosis

X Hu, Z Wang, C Kong, Y Wang, W Zhu… - Frontiers in …, 2022 - frontiersin.org
Multiple causes may contribute to osteoporosis, characterized by a loss in bone mass and
density as a consequence of the degradation of bone microstructure and a resultant rise in …

[HTML][HTML] Cytoplasmic and nuclear functions of cIAP1

A Zadoroznyj, L Dubrez - Biomolecules, 2022 - mdpi.com
Cellular inhibitor of apoptosis 1 (cIAP1) is a cell signaling regulator of the IAP family.
Through its E3-ubiquitine ligase activity, it has the ability to activate intracellular signaling …

[HTML][HTML] TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan

E Håland, IN Moen, E Veidal, H Hella, K Misund… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is an incurable cancer caused by malignant transformation of
plasma cells. Transforming growth factor-β activated kinase 1 (MAP3K7, TAK1) is a major …

[HTML][HTML] Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk* MYC mouse myeloma

NY Villa, MM Rahman, J Mamola, ME Sharik… - Oncotarget, 2022 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is a hematological malignancy of plasma cells that remains
incurable despite significant progress with myeloablative regimens and autologous stem cell …

A Novel Necroptosis-Related Signature Can Predict Prognosis and Chemotherapy Sensitivity in Multiple Myeloma

JY Jiang, FY Yao, J Liu, XL Wang… - … in Cancer Research …, 2024 - journals.sagepub.com
Background Necroptosis is an inflammatory cell death mode, and its association with
multiple myeloma (MM) remains unclear. Methods This prospective study first analyzed the …

假体周围骨溶解中的新型细胞程序性死亡

梁晓龙, 郑恺, 耿德春, 徐耀增 - 中国组织工程研究, 2024 - cjter.com
假体周围骨溶解中的新型细胞程序性死亡 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 28|No.21|July 2024|3393 中国组织工程研究 Chinese Journal of Tissue …

Novel programmed cell death in periprosthetic osteolysis

X Liang, K Zheng, D Geng, Y Xu - Chinese Journal of Tissue Engineering …, 2024 - cjter.com
BACKGROUND: In addition to apoptosis, recent studies have discovered novel forms of
programmed cell death in periprosthetic osteolysis, which is involved in regulating local …

SMAC-mimetic induced cell death in LPS-pretreated human macrophages

MN Holter-Sørensen - 2021 - ntnuopen.ntnu.no
Betennelse er en biologisk respons i kroppsvevet forårsaket av skadelig stimuli. For å
opprettholde homeostase i kroppen er det viktig å nøye regulere immuncellene. Dysregulert …

[HTML][HTML] Pharmaceutical targeting of RIPK1-signaling: Characterization of cell death in human macrophage systems and therapeutic potential in multiple myeloma

IN Moen - 2021 - ntnuopen.ntnu.no
The receptor-interacting protein kinase 1 (RIPK1)-pathway is a key regulator of inflammation
and cell death. RIPK1-dependent cell death has been well studied in murine macrophages …