Recent advances in acoustofluidic separation technology in biology

Y Fan, X Wang, J Ren, F Lin, J Wu - Microsystems & Nanoengineering, 2022 - nature.com
Acoustofluidic separation of cells and particles is an emerging technology that integrates
acoustics and microfluidics. In the last decade, this technology has attracted significant …

Unconventional acoustic approaches for localized and designed micromanipulation

K Kolesnik, M Xu, PVS Lee, V Rajagopal, DJ Collins - Lab on a Chip, 2021 - pubs.rsc.org
Acoustic fields are ideal for micromanipulation, being biocompatible and with force gradients
approaching the scale of single cells. They have accordingly found use in a variety of …

High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy

B Kang, J Shin, HJ Park, C Rhyou, D Kang… - Nature …, 2018 - nature.com
The fabrication of functional tissues is essential for clinical applications such as disease
treatment and drug discovery. Recent studies have revealed that the mechanical …

Controllable fusion of human brain organoids using acoustofluidics

Z Ao, H Cai, Z Wu, J Ott, H Wang, K Mackie, F Guo - Lab on a Chip, 2021 - pubs.rsc.org
The fusion of human organoids holds promising potential in modeling physiological and
pathological processes of tissue genesis and organogenesis. However, current fused …

A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers

S Zhao, M Wu, S Yang, Y Wu, Y Gu, C Chen, J Ye… - Lab on a Chip, 2020 - pubs.rsc.org
Separation of nano/microparticles based on surface acoustic waves (SAWs) has shown
great promise for biological, chemical, and medical applications ranging from sample …

High-throughput acoustofluidic fabrication of tumor spheroids

B Chen, Y Wu, Z Ao, H Cai, A Nunez, Y Liu, J Foley… - Lab on a Chip, 2019 - pubs.rsc.org
Three-dimensional (3D) culture of multicellular spheroids, offering a desirable biomimetic
microenvironment, is appropriate for recapitulating tissue cellular adhesive complexity and …

Self-contained microfluidic systems: a review

M Boyd-Moss, S Baratchi, M Di Venere… - Lab on a Chip, 2016 - pubs.rsc.org
Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and
health conditions using small amounts of biological samples and reagents. Despite these …

Detachable acoustofluidic system for particle separation via a traveling surface acoustic wave

Z Ma, DJ Collins, Y Ai - Analytical chemistry, 2016 - ACS Publications
Components in biomedical analysis tools that have direct contact with biological samples,
especially biohazardous materials, are ideally discarded after use to prevent cross …

Understanding immune‐driven brain aging by human brain organoid microphysiological analysis platform

Z Ao, S Song, C Tian, H Cai, X Li, Y Miao… - Advanced …, 2022 - Wiley Online Library
The aging of the immune system drives systemic aging and the pathogenesis of age‐related
diseases. However, a significant knowledge gap remains in understanding immune‐driven …

Selective manipulation of microscopic particles with precursor swirling Rayleigh waves

A Riaud, M Baudoin, O Bou Matar, L Becerra… - Physical Review …, 2017 - APS
Contactless manipulation of microparticles is demonstrated with single-beam acoustical
tweezers based on precursor swirling Rayleigh waves. These surface waves degenerate …