Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

Spinal cord injury (SCI) involves diverse injury responses in different cell types in a
temporally and spatially specific manner. Here, using single-cell transcriptomic analyses …

Background Postoperative cognitive decline (POCD) is a recognized clinical phenomenon
characterized by cognitive impairments in patients following anesthesia and surgery, yet its …

Globally, neurodegenerative diseases cause a significant degree of disability and distress.
Brain-derived neurotrophic factor (BDNF), primarily found in the brain, has a substantial role …

Ferroptosis is an iron-and lipid peroxidation (LPO)-mediated programmed cell death type.
Recently, mounting evidence has indicated the involvement of ferroptosis in …

Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …