[HTML][HTML] The effects of stress exposure on prefrontal cortex: Translating basic research into successful treatments for post-traumatic stress disorder

AFT Arnsten, MA Raskind, FB Taylor, DF Connor - Neurobiology of stress, 2015 - Elsevier
Research on the neurobiology of the stress response in animals has led to successful new
treatments for Post-Traumatic Stress Disorder (PTSD) in humans. Basic research has found …

Psychological and biological mechanisms linking trauma with cardiovascular disease risk

JA Sumner, S Cleveland, T Chen, JL Gradus - Translational psychiatry, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and
experiences of psychological trauma have been associated with subsequent CVD onset …

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress

M Picard, MJ McManus, JD Gray… - Proceedings of the …, 2015 - National Acad Sciences
The experience of psychological stress triggers neuroendocrine, inflammatory, metabolic,
and transcriptional perturbations that ultimately predispose to disease. However, the …

Single-prolonged stress: a review of two decades of progress in a rodent model of post-traumatic stress disorder

MJ Lisieski, AL Eagle, AC Conti, I Liberzon… - Frontiers in …, 2018 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric
condition. However, the biological mechanisms underlying this disease are still largely …

Metabolism, metabolomics, and inflammation in posttraumatic stress disorder

SH Mellon, A Gautam, R Hammamieh, M Jett… - Biological …, 2018 - Elsevier
Posttraumatic stress disorder (PTSD) is defined by classic psychological manifestations,
although among the characteristics are significantly increased rates of serious somatic …

Oxidative stress in anxiety and comorbid disorders

I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

Offspring psychological and biological correlates of parental posttraumatic stress: Review of the literature and research agenda

EW Leen-Feldner, MT Feldner, A Knapp… - Clinical psychology …, 2013 - Elsevier
Millions of individuals with posttraumatic stress disorder (PTSD) are parents. A burgeoning
literature suggests that offspring of parents with this condition may be at increased risk for …

Traumatic stress, oxidative stress and post-traumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis

MW Miller, N Sadeh - Molecular psychiatry, 2014 - nature.com
Post-traumatic stress disorder (PTSD) is associated with elevated risk for a variety of age-
related diseases and neurodegeneration. In this paper, we review evidence relevant to the …

Stress, PTSD, and dementia

MS Greenberg, K Tanev, MF Marin… - Alzheimer's & …, 2014 - Wiley Online Library
The physiological consequences of acute and chronic stress on a range of organ systems
have been well documented after the pioneering work of Hans Selye more than 70 years …

Sex differences: Transcriptional signatures of stress exposure in male and female brains

E Brivio, JP Lopez, A Chen - Genes, brain and behavior, 2020 - Wiley Online Library
More than two‐thirds of patients suffering from stress‐related disorders are women but over
two‐thirds of suicide completers are men. These are just some examples of the many sex …